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Details
Link-It Detail - Disease - Fasciculation
Debug Stats
  • ### Total Build Time: 45 ms 23.474 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 575 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 184 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 564 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 2.825 KB
  • CONCEPT_RELATIONSHIPS gt=22 ms Completed: 22 ms rowSize= 6.366 KB
  • CONCEPT_GENES gt=7 ms Completed: 7 ms rowSize= 11.491 KB
  • CONCEPT_XREFS gt=6 ms Completed: 6 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Fasciculation C0015644
Definition (1)
Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations can often by visualized and take the form of a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
Semantic Types (1)
Sign or Symptom (T184)
Parents (1)
img Neuromuscular Manifestations C0752252
Ancestral Roots
RootRoot Plus OneDepthParent
img Pathological Conditions, Signs and Symptoms C0039058img Signs and Symptoms C00370885img Neuromuscular Manifestations C0752252
img Nervous System Diseases C0027765img Neurologic Manifestations C00278544img Neuromuscular Manifestations C0752252
Relationships (13)

Relation Types:
diso_​to_​anat : 1
diso_​to_​chem : 4
diso_​to_​diso : 7
diso_​to_​phys : 1


Relationships:
none : 9
isa : 2
replaces : 1
used_​for : 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO15img Amyotrophic Lateral Sclerosis C0002736
DISO_to_DISO9img chemically induced C0007994
DISO_to_CHEM8img Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(N,N,N-trimethyl)- C0038627
DISO_to_CHEM8img Succinylcholine C0038627
DISO_to_ANAT7img Muscle, Skeletal C0242692
DISO_to_DISO6img chemically induced C0007994
DISO_to_CHEM5img Agents, Curare-Like C0010464
DISO_to_CHEM5img Neuromuscular Depolarizing Agents C0027867
DISO_to_PHYS5img Action Potentials C0001272
DISO_to_DISOisaimg FASCICULATION, TONGUE C0239548
DISO_to_DISOreplacesimg Fasciculation C0015644
DISO_to_DISOused_forimg MANIFESTATIONS NEUROL C0027854
DISO_to_DISOisaimg O/E - muscular fasciculation C0437277
Genes (13)

Species:
human : 13
SpeciesGeneGeneIdGene NameEvidence
HumanVAPB9217VAMP (vesicle-associated membrane protein)-associated protein B and C
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanSOD16647superoxide dismutase 1, soluble
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanATXN26311ataxin 2
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanPSAP5660prosaposin
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanPRPH5630peripherin
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanNEFH4744neurofilament, heavy polypeptide
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanATXN34287ataxin 3
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanNBR14077neighbor of BRCA1 gene 1
img GENERIF, Score=1000, Pubmed Id: 11856312, UMLKSK CUI: C0015644
HumanHSPB13315heat shock 27kDa protein 1
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanHEXB3074hexosaminidase B (beta polypeptide)
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanDCTN11639dynactin 1
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanAR367androgen receptor
img OMIM, Score=1000, UMLKSK CUI: C0015644
HumanANG283angiogenin, ribonuclease, RNase A family, 5
img OMIM, Score=1000, UMLKSK CUI: C0015644
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0015644Fasciculation0self