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Details
Link-It Detail - Disease - Encephalomyelitis, Autoimmune, Experimental
Debug Stats
  • ### Total Build Time: 38 ms 25.889 KB
  • CONCEPT_NAME gt=15 ms Completed: 15 ms rowSize= 384 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 768 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 198 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.015 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 9.373 KB
  • CONCEPT_RELATIONSHIPS gt=17 ms Completed: 17 ms rowSize= 12.927 KB
  • CONCEPT_GENES gt=1 ms Completed: 1 ms rowSize= 45 bytes
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.177 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Encephalomyelitis, Autoimmune, Experimental C0014072
Definition (1)
An autoimmune demyelinating disease of the central nervous system that is produced experimentally in animals by the injection of homogenized brain or spinal cord in Freund's adjuvant. Myelin basic protein appears to be the antigen that elicits the hypersensitivity immune response which is characterized by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Experimental allergic encephalomyelitis (EAE) is used as an animal model for demyelinating diseases of the human central nervous system such as multiple sclerosis.
Semantic Types (1)
Experimental Model of Disease (T050)
Parents (2)
img Nervous System Autoimmune Disease, Experimental C0752090
img Demyelinating Autoimmune Diseases, CNS C0751873
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Autoimmune Diseases C00043645img Nervous System Autoimmune Disease, Experimental C0752090
img Nervous System Diseases C0027765img Autoimmune Diseases of the Nervous System C07518714img Nervous System Autoimmune Disease, Experimental C0752090
img Nervous System Diseases C0027765img Demyelinating Diseases C00113034img Demyelinating Autoimmune Diseases, CNS C0751873
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Demyelinating Autoimmune Diseases, CNS C0751873
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076826img Demyelinating Autoimmune Diseases, CNS C0751873
img Immune System Diseases C0021053img Autoimmune Diseases C00043645img Demyelinating Autoimmune Diseases, CNS C0751873
img Nervous System Diseases C0027765img Autoimmune Diseases of the Nervous System C07518714img Demyelinating Autoimmune Diseases, CNS C0751873
Relationships (124)

Relation Types:
diso_​to_​anat : 42
diso_​to_​chem : 50
diso_​to_​diso : 19
diso_​to_​phen : 2
diso_​to_​phys : 11


Relationships:
none : 123
entry_​version_​of : 1
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO260img Multiple Sclerosis C0026769
DISO_to_PHEN209img genetic aspects C0017399
DISO_to_PHEN169img genetic aspects C0017399
DISO_to_DISO166img Multiple Sclerosis C0026769
DISO_to_DISO159img chemically induced C0007994
DISO_to_ANAT119img T-Lymphocyte C0039194
DISO_to_ANAT115img Regulatory T-Lymphocytes C0039198
DISO_to_ANAT114img Central Nervous System C0927232
DISO_to_ANAT93img T-Lymphocyte C0039194
DISO_to_ANAT90img Spinal Cord C0037925
DISO_to_DISO86img chemically induced C0007994
DISO_to_CHEM85img Interleukin-17 C0384648
DISO_to_ANAT76img CD4 Positive T Lymphocytes C0039215
DISO_to_ANAT68img Spinal Cord C0037925
DISO_to_ANAT61img Brain C0006104
DISO_to_ANAT61img Central Nervous System C0927232
DISO_to_ANAT61img Helper-Inducer T-Lymphocyte C0018894
DISO_to_ANAT61img T-Lymphocyte Subsets C0080202
DISO_to_ANAT55img Brain C0006104
DISO_to_CHEM55img Fragments, Peptide C0030935
DISO_to_ANAT54img T-helper cell type 1 C0242632
DISO_to_DISO53img Autoimmune Status C0004368
DISO_to_ANAT52img Cell, Th17 C2936411
DISO_to_ANAT52img Dendritic Cells C0011306
DISO_to_CHEM47img Immunosuppressive Agents C0021081
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0014072Encephalomyelitis, Autoimmune, Experimental0self