Human | CCR2 | 729230 | chemokine (C-C motif) receptor 2 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | NEWENTRY | 192343 | Record to support submission of GeneRIFs for a gene not in Gene (human; man). | An effective and highly specific interaction of the surface glycoprotein E domain II (DII) of the tick born encephalitis and Dengue viruses with the laminin binding protein (LBP), is shown.[LBP] |
Human | UNC93B1 | 81622 | unc-93 homolog B1 (C. elegans) | findings elucidate a genetic etiology for herpes simplex virus encephalitis in two children with autosomal recessive deficiency in the intracellular protein UNC-93B, resulting in impaired cellular interferon-alpha/beta and -lambda antiviral responses |
Human | IL32 | 9235 | interleukin 32 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | BRSK2 | 9024 | BR serine/threonine kinase 2 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | RFXANK | 8625 | regulatory factor X-associated ankyrin-containing protein | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | ZNF175 | 7728 | zinc finger protein 175 | OTK18/zinc finger protein 175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis |
Human | VEGFA | 7422 | vascular endothelial growth factor A | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | TYRP1 | 7306 | tyrosinase-related protein 1 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | TNF | 7124 | tumor necrosis factor | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | TLR3 | 7098 | toll-like receptor 3 | study reports a dominant-negative TLR3 allele in otherwise healthy children with herpes simplex virus 1 encephalitis; TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS |
Human | TIMP1 | 7076 | TIMP metallopeptidase inhibitor 1 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | CCL3 | 6348 | chemokine (C-C motif) ligand 3 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | SAT1 | 6303 | spermidine/spermine N1-acetyltransferase 1 | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | RFXAP | 5994 | regulatory factor X-associated protein | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | RFX5 | 5993 | regulatory factor X, 5 (influences HLA class II expression) | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | EIF2AK2 | 5610 | eukaryotic translation initiation factor 2-alpha kinase 2 | viral-induced PKR activation may play a significant role in pathogenesis by mediating the host response to poliovirus encephalitis |
Human | MOG | 4340 | myelin oligodendrocyte glycoprotein | identification of T cell epitopes that are encephalitogenic and presented by B cells |
Human | MMP9 | 4318 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | CIITA | 4261 | class II, major histocompatibility complex, transactivator | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | MBP | 4155 | myelin basic protein | T cells specific for low-affinity MHC-binding hMBP epitopes and hMBP82-100-specific type B T cells were highly encephalitogenic |
Human | MAG | 4099 | myelin associated glycoprotein | Myelin destruction with preferential loss of MAG is found in autopsy brains with acute white matter ischemia as well as in HSV- and CMV-encephalitis |
Human | SH2D1A | 4068 | SH2 domain containing 1A | |
Human | LTF | 4057 | lactotransferrin | INFERRED, Score=800, UMLKSK CUI: C0014038 |
Human | IL10 | 3586 | interleukin 10 | INFERRED, Score=800, UMLKSK CUI: C0014038 |