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Details
Link-It Detail - Disease - Dry Eye Syndromes
Debug Stats
  • ### Total Build Time: 61 ms 37.044 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 332 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 475 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 563 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.397 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.514 KB
  • CONCEPT_RELATIONSHIPS gt=30 ms Completed: 30 ms rowSize= 14.026 KB
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 17.406 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.151 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dry Eye Syndromes C0013238
Definition (1)
Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Lacrimal Apparatus Diseases C0022904
Children (3)
img Keratoconjunctivitis Sicca C0022575
img Sjogrens Syndrome C1527336
img Xerophthalmia C0043349
Ancestral Roots
RootRoot Plus OneDepthParent
img Eye Diseases C0015397img Lacrimal Apparatus Diseases C00229043img Lacrimal Apparatus Diseases C0022904
Relationships (115)

Relation Types:
diso_​to_​anat : 17
diso_​to_​chem : 60
diso_​to_​diso : 34
diso_​to_​phen : 1
diso_​to_​phys : 3


Relationships:
none : 50
classifies : 1
is_​associated_​anatomic_​site_​of : 1
isa : 1
mapped_​to : 9
may_​treat : 51
parent_​is_​cdrh : 1
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_ANAT194img Tears C0039409
DISO_to_ANAT94img Tears C0039409
DISO_to_CHEM84img Ophthalmic Solutions C0029083
DISO_to_CHEM58img Ophthalmic Solution C0029083
DISO_to_ANAT57img Lacrimal Apparatus C0022903
DISO_to_ANAT56img Conjunctiva C0009758
DISO_to_ANAT54img Cornea C0010031
DISO_to_ANAT53img Lacrimal Apparatus C0022903
DISO_to_DISO49img Complication Aspects C1171258
DISO_to_ANAT44img Cornea C0010031
DISO_to_CHEM41img Cyclosporine C0010592
DISO_to_DISO39img Complication Aspects C1171258
DISO_to_ANAT37img Meibomian Glands C0025181
DISO_to_DISO33img chemically induced C0007994
DISO_to_CHEM32img Immunosuppressive Agents C0021081
DISO_to_DISO31img Animal Disease Models C0012644
DISO_to_DISO31img Corneal Diseases C0010034
DISO_to_ANAT27img Epithelium, Corneal C0459875
DISO_to_ANAT26img Conjunctiva C0009758
DISO_to_DISO24img A-760-766 DISORDERS OF THE EYELIDS C0015423
DISO_to_DISO23img Corneal Diseases C0010034
DISO_to_PHEN22img genetic aspects C0017399
DISO_to_DISO21img Conjunctival Diseases C0009759
DISO_to_ANAT19img Eyelid structure C0015426
DISO_to_CHEM18img Cyclosporine C0010592
Genes (61)

Species:
human : 61
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanISCA181689iron-sulfur cluster assembly 1
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanAICDA57379activation-induced cytidine deaminase
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanIL23A51561interleukin 23, alpha subunit p19
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanFOXP350943forkhead box P3
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanIGK@50802
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanCD27429126CD274 molecule
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanPTPN2226191protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanHMHA123526histocompatibility (minor) HA-1
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanMALT110892mucosa associated lymphoid tissue lymphoma translocation gene 1
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanGRAP10750GRB2-related adaptor protein
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTNFSF13B10673tumor necrosis factor (ligand) superfamily, member 13b
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanCXCL1310563chemokine (C-X-C motif) ligand 13
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanCRISP310321cysteine-rich secretory protein 3
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTNFSF138741tumor necrosis factor (ligand) superfamily, member 13
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanXDH7498xanthine dehydrogenase
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTXN7295thioredoxin
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTGFB17040transforming growth factor, beta 1
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTRB@6957
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTAP26891transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanSTAT36774signal transducer and activator of transcription 3 (acute-phase response factor)
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanTRIM216737tripartite motif containing 21
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanMAP2K46416mitogen-activated protein kinase kinase 4
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanCCL216366chemokine (C-C motif) ligand 21
INFERRED, Score=800, UMLKSK CUI: C0013238
HumanRBBP45928retinoblastoma binding protein 4
INFERRED, Score=800, UMLKSK CUI: C0013238
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0013238Dry Eye Syndromes0self