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Details
Link-It Detail - Disease - Diabetic Nephropathies
Debug Stats
  • ### Total Build Time: 145 ms 59.471 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 342 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 378 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 991 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 5.377 KB
  • CONCEPT_RELATIONSHIPS gt=113 ms Completed: 113 ms rowSize= 15.564 KB
  • CONCEPT_GENES gt=25 ms Completed: 25 ms rowSize= 35.483 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.156 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Diabetic Nephropathies C0011881
Definition (1)
kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney; features include increased urine protein and declining kidney function.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Diabetes Complications C0342257
img Kidney Diseases C0022658
Ancestral Roots
RootRoot Plus OneDepthParent
img Endocrine System Diseases C0014130img Diabetes Mellitus C00118494img Diabetes Complications C0342257
img Nutritional and Metabolic Diseases C0028715img Metabolic Diseases C00255176img Diabetes Complications C0342257
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208875img Kidney Diseases C0022658
img Male Urogenital Diseases C1720894img Urologic Diseases C00420754img Kidney Diseases C0022658
Relationships (262)

Relation Types:
diso_​to_​anat : 18
diso_​to_​chem : 158
diso_​to_​diso : 72
diso_​to_​gene : 2
diso_​to_​phen : 2
diso_​to_​phys : 10


Relationships:
none : 146
associated_​with : 2
classified_​as : 4
clinically_​similar : 3
is_​associated_​anatomic_​site_​of : 2
is_​finding_​of_​disease : 1
isa : 7
location_​of : 1
mapped_​to : 2
may_​prevent : 30
may_​treat : 62
related_​to : 2
Page Size
Current 25
  Page 1 of 11
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO833img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_DISO682img Diabetes Mellitus, Non-Insulin-Dependent C0011860
DISO_to_PHEN441img genetic aspects C0017399
DISO_to_DISO389img Complication Aspects C1171258
DISO_to_DISO378img Diabetes Mellitus, Insulin-Dependent C0011854
DISO_to_ANAT374img In Blood C0005768
DISO_to_DISO352img Kidney Failure, Chronic C0022661
DISO_to_DISO331img Diabetes Mellitus, Insulin-Dependent C0011854
DISO_to_DISO317img Complication Aspects C1171258
DISO_to_DISO309img Kidney Failure, Chronic C0022661
DISO_to_DISO304img DIABETES MELLITUS EXPER C0011853
DISO_to_ANAT280img Kidney C0022646
DISO_to_PHEN277img genetic aspects C0017399
DISO_to_DISO250img Albuminuria C0001925
DISO_to_ANAT242img In Blood C0005768
DISO_to_DISO195img Albuminuria C0001925
DISO_to_CHEM175img Angiotensin-Converting Enzyme Inhibitors C0003015
DISO_to_DISO162img Hypertension C0020538
DISO_to_ANAT152img Kidney C0022646
DISO_to_CHEM148img Antihypertensive Agents C0003364
DISO_to_DISO144img DIABETES MELLITUS EXPER C0011853
DISO_to_CHEM128img Angiotensin II Type 1 Receptor Blockers C1449680
DISO_to_DISO123img Angiopathies, Diabetic C0011875
DISO_to_DISO110img Hypertension C0020538
DISO_to_CHEM105img Agents, Antihyperglycemic C0020616
Genes (100)

Species:
human : 100
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanSUMO4387082small ubiquitin-like modifier 4
img GENERIF, Score=1000, Pubmed Id: 17660269, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 17229939, UMLKSK CUI: C0011881
HumanPLEKHH2130271pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
img GENERIF, Score=1000, Pubmed Id: 18752002, UMLKSK CUI: C0011881
HumanAPOA5116519apolipoprotein A-V
img GENERIF, Score=1000, Pubmed Id: 17493548, UMLKSK CUI: C0011881
HumanCNDP184735carnosine dipeptidase 1 (metallopeptidase M20 family)
img GENERIF, Score=1000, Pubmed Id: 18753673, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 17601992, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 17205963, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 17601991, UMLKSK CUI: C0011881
HumanNCALD83988neurocalcin delta
img GENERIF, Score=1000, Pubmed Id: 17671797, UMLKSK CUI: C0011881
HumanXYLT264132xylosyltransferase II
img GENERIF, Score=1000, Pubmed Id: 16164625, UMLKSK CUI: C0011881
HumanXYLT164131xylosyltransferase I
img GENERIF, Score=1000, Pubmed Id: 16164625, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 17003309, UMLKSK CUI: C0011881
HumanACE259272angiotensin I converting enzyme 2
img GENERIF, Score=1000, Pubmed Id: 18223023, UMLKSK CUI: C0011881
img GENERIF, Score=861, Pubmed Id: 18389211, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 16211375, UMLKSK CUI: C0011881
HumanLRRC757554leucine rich repeat containing 7
img GENERIF, Score=1000, Pubmed Id: 17968527, UMLKSK CUI: C0011881
HumanCNDP255748CNDP dipeptidase 2 (metallopeptidase M20 family)
img GENERIF, Score=1000, Pubmed Id: 18753673, UMLKSK CUI: C0011881
HumanKIRREL55243kin of IRRE like (Drosophila)
img GENERIF, Score=1000, Pubmed Id: 17968527, UMLKSK CUI: C0011881
HumanTHG1L54974tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
img GENERIF, Score=1000, Pubmed Id: 18508967, UMLKSK CUI: C0011881
HumanGHRL51738ghrelin/obestatin prepropeptide
img GENERIF, Score=1000, Pubmed Id: 16793966, UMLKSK CUI: C0011881
HumanNOX350508NADPH oxidase 3
img GENERIF, Score=1000, Pubmed Id: 17336700, UMLKSK CUI: C0011881
HumanANKRD127063ankyrin repeat domain 1 (cardiac muscle)
img GENERIF, Score=1000, Pubmed Id: 17239933, UMLKSK CUI: C0011881
HumanGREM126585gremlin 1, DAN family BMP antagonist
img GENERIF, Score=1000, Pubmed Id: 15957132, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 17980714, UMLKSK CUI: C0011881
HumanHPSE10855heparanase
img GENERIF, Score=901, Pubmed Id: 17051139, UMLKSK CUI: C0011881
img GENERIF, Score=1000, Pubmed Id: 15983219, UMLKSK CUI: C0011881
HumanELMO19844engulfment and cell motility 1
img GENERIF, Score=1000, Pubmed Id: 15793258, UMLKSK CUI: C0011881
HumanADIPOQ9370adiponectin, C1Q and collagen domain containing
img GENERIF, Score=1000, Pubmed Id: 17490776, UMLKSK CUI: C0011881
HumanTSC22D18848TSC22 domain family, member 1
img GENERIF, Score=1000, Pubmed Id: 12757981, UMLKSK CUI: C0011881
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
img GENERIF, Score=901, Pubmed Id: 18287563, UMLKSK CUI: C0011881
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
img GENERIF, Score=1000, Pubmed Id: 17968527, UMLKSK CUI: C0011881
HumanVEGFA7422vascular endothelial growth factor A
Click here to display 6 evidence detail records.
HumanUCP37352uncoupling protein 3 (mitochondrial, proton carrier)
img GENERIF, Score=1000, Pubmed Id: 15120704, UMLKSK CUI: C0011881
HumanUCP27351uncoupling protein 2 (mitochondrial, proton carrier)
img GENERIF, Score=1000, Pubmed Id: 15120704, UMLKSK CUI: C0011881
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0011881Diabetic Nephropathies0self