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Details
Link-It Detail - Disease - Dermatitis, Atopic
Debug Stats
  • ### Total Build Time: 566 ms 61.389 KB
  • CONCEPT_NAME gt=6 ms Completed: 6 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 382 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=19 ms Completed: 19 ms rowSize= 1.831 KB
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 6.677 KB
  • CONCEPT_RELATIONSHIPS gt=490 ms Completed: 490 ms rowSize= 14.738 KB
  • CONCEPT_GENES gt=45 ms Completed: 45 ms rowSize= 36.072 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=2 ms Completed: 2 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dermatitis, Atopic C0011615
Definition (1)
chronic inflammatory skin disorder in individuals with a hereditary predisposition to a lowered threshold to pruritus; characterized by extreme itching, leading to scratching and rubbing that result in typical lesions of eczema.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (4)
img Hypersensitivity, Immediate C0020523
img Skin Diseases, Eczematous C0162817
img Skin Diseases, Genetic C0037277
img Dermatitis C0011603
Ancestral Roots
RootRoot Plus OneDepthParent
img Immune System Diseases C0021053img Hypersensitivity C00205174img Hypersensitivity, Immediate C0020523
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Skin Diseases, Eczematous C0162817
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Skin Diseases, Genetic C0037277
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Genetic Diseases, Inborn C09501234img Skin Diseases, Genetic C0037277
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Dermatitis C0011603
Relationships (276)

Relation Types:
diso_​to_​anat : 23
diso_​to_​chem : 134
diso_​to_​diso : 104
diso_​to_​gene : 2
diso_​to_​phen : 2
diso_​to_​phys : 11


Relationships:
none : 135
associated_​with : 4
isa : 22
location_​of : 1
manifestation_​of : 27
mapped_​to : 1
may_​treat : 84
permuted_​term_​of : 1
related_​to : 1
Page Size
Current 25
  Page 1 of 12
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_PHEN347img genetic aspects C0017399
DISO_to_DISO268img Complication Aspects C1171258
DISO_to_DISO215img Complication Aspects C1171258
DISO_to_ANAT214img Skin C1123023
DISO_to_CHEM209img Tacrolimus C0085149
DISO_to_PHEN189img genetic aspects C0017399
DISO_to_CHEM181img Immunosuppressive Agents C0021081
DISO_to_ANAT170img In Blood C0005768
DISO_to_ANAT165img In Blood C0005768
DISO_to_CHEM144img Immunosuppressive Agents C0021081
DISO_to_DISO137img Asthma C0004096
DISO_to_CHEM133img Tacrolimus C0085149
DISO_to_CHEM126img Immunoglobulin E C0020846
DISO_to_DISO124img Asthma C0004096
DISO_to_DISO123img Dog Diseases C0012979
DISO_to_CHEM117img AGENT DERMATOL C0011625
DISO_to_ANAT113img Skin C1123023
DISO_to_DISO107img CANINE DIS C0012979
DISO_to_CHEM105img Allergens C0002092
DISO_to_CHEM103img Immunoglobulin E C0020846
DISO_to_CHEM100img Intermediate Filament Proteins C0021769
DISO_to_DISO99img PSORIASIS C0033860
DISO_to_CHEM96img AGENT DERMATOL C0011625
DISO_to_DISO95img Food Allergy C0016470
DISO_to_CHEM90img Allergens C0002092
Genes (92)

Species:
human : 92
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanNPSR1387129neuropeptide S receptor 1
img GENERIF, Score=1000, Pubmed Id: 15990798, UMLKSK CUI: C0011615
HumanIL31386653interleukin 31
img GENERIF, Score=673, Pubmed Id: 16461143, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 18678344, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 15925362, UMLKSK CUI: C0011615
HumanCOL6A5256076collagen, type VI, alpha 5
img GENERIF, Score=673, Pubmed Id: 17850181, UMLKSK CUI: C0011615
HumanDCD117159dermcidin
img GENERIF, Score=1000, Pubmed Id: 15944307, UMLKSK CUI: C0011615
HumanTSLP85480thymic stromal lymphopoietin
img GENERIF, Score=901, Pubmed Id: 18768889, UMLKSK CUI: C0011615
HumanITCH83737itchy E3 ubiquitin protein ligase
img GENERIF, Score=1000, Pubmed Id: 19001863, UMLKSK CUI: C0011615
HumanADM279924adrenomedullin 2
img GENERIF, Score=734, Pubmed Id: 17008878, UMLKSK CUI: C0011615
HumanDEFB103B55894defensin, beta 103B
img GENERIF, Score=734, Pubmed Id: 17415576, UMLKSK CUI: C0011615
HumanTLR954106toll-like receptor 9
img GENERIF, Score=734, Pubmed Id: 17573724, UMLKSK CUI: C0011615
HumanPHF1151131PHD finger protein 11
img GAD, Score=1000, Pubmed Id: 15674390, UMLKSK CUI: C0011615
HumanHAVCR126762hepatitis A virus cellular receptor 1
img GENERIF, Score=734, Pubmed Id: 14637143, UMLKSK CUI: C0011615
HumanGPR4411251prostaglandin D2 receptor 2
img GENERIF, Score=1000, Pubmed Id: 12230502, UMLKSK CUI: C0011615
HumanSPINK511005serine peptidase inhibitor, Kazal type 5
img GAD, Score=716, Pubmed Id: 11544479, UMLKSK CUI: C0011615
img GAD, Score=1000, Pubmed Id: 12752122, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 14551605, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 11796258, UMLKSK CUI: C0011615
HumanCCL2710850chemokine (C-C motif) ligand 27
img GENERIF, Score=1000, Pubmed Id: 15335355, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 14767451, UMLKSK CUI: C0011615
HumanCYSLTR110800cysteinyl leukotriene receptor 1
img GENERIF, Score=1000, Pubmed Id: 16846449, UMLKSK CUI: C0011615
HumanTBC1D49882TBC1 domain family, member 4
img GENERIF, Score=1000, Pubmed Id: 15304337, UMLKSK CUI: C0011615
HumanIL1RL19173interleukin 1 receptor-like 1
img GENERIF, Score=1000, Pubmed Id: 16118232, UMLKSK CUI: C0011615
HumanTNFSF188995tumor necrosis factor (ligand) superfamily, member 18
img GENERIF, Score=734, Pubmed Id: 16955181, UMLKSK CUI: C0011615
HumanTNFRSF148764tumor necrosis factor receptor superfamily, member 14
img GENERIF, Score=1000, Pubmed Id: 14749527, UMLKSK CUI: C0011615
HumanEPX8288eosinophil peroxidase
img GENERIF, Score=734, Pubmed Id: 19014520, UMLKSK CUI: C0011615
HumanVIP7432vasoactive intestinal peptide
img GENERIF, Score=673, Pubmed Id: 12670727, UMLKSK CUI: C0011615
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 16456664, UMLKSK CUI: C0011615
HumanTNF7124tumor necrosis factor
img GENERIF, Score=734, Pubmed Id: 15560757, UMLKSK CUI: C0011615
HumanTLR27097toll-like receptor 2
img GENERIF, Score=1000, Pubmed Id: 15007364, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 18234309, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 17531301, UMLKSK CUI: C0011615
img GENERIF, Score=1000, Pubmed Id: 18445187, UMLKSK CUI: C0011615
HumanTGFB17040transforming growth factor, beta 1
img GAD, Score=1000, Pubmed Id: 11496247, UMLKSK CUI: C0011615
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0011615Dermatitis, Atopic0self