Logo arc image image
GATACA
  • Pin/Unpin Search
  • Pin/Unpin Details
Status:
Global Actions
Concepts: 0 (0)   Selected: 0 (0
Clear All Selections
 
Search
Text Search Results
Text Search Query:
none
Text Search Options:
none

Guided Help

Text Search Results
GraphTree Minimize or Maximize this Category
 Disease: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Anatomy: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Gene: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Jax Mouse Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Human Phenotype: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Biological Processes: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Cellular Component: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Gene Ontology: Molecular Function: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Pathway: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 Drug: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Genomic Expression Atlas --
      Microarray Datasets: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 PubMed: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
GraphTree Minimize or Maximize this Category
 CoExpression Atlas: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 CoExpression: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Minimize or Maximize this Category
 Interactions: 0
No results.
 Concepts (w/Genes): 0 (0)   Selected (w/genes): 0 (0)
Details
Link-It Detail - Disease - Dental Caries
Debug Stats
  • ### Total Build Time: 282 ms 42.976 KB
  • CONCEPT_NAME gt=15 ms Completed: 14 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 679 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=1 ms Completed: 0 ms rowSize= 558 bytes
  • CONCEPT_CHILDREN gt=9 ms Completed: 9 ms rowSize= 982 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.507 KB
  • CONCEPT_RELATIONSHIPS gt=218 ms Completed: 218 ms rowSize= 14.322 KB
  • CONCEPT_GENES gt=34 ms Completed: 34 ms rowSize= 23.305 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dental Caries C0011334
Definition (1)
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. The three most prominent theories used to explain the etiology of the disease are that acids produced by bacteria lead to decalcification; that micro-organisms destroy the enamel protein; or that keratolytic micro-organisms produce chelates that lead to decalcification.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (1)
img Tooth Demineralization C0085511
Children (2)
img Dental Fissures C0011360
img Root Caries C0162644
Ancestral Roots
RootRoot Plus OneDepthParent
img Stomatognathic Diseases C0038368img Tooth Diseases C00404354img Tooth Demineralization C0085511
Relationships (172)

Relation Types:
diso_​to_​anat : 17
diso_​to_​chem : 96
diso_​to_​diso : 54
diso_​to_​phen : 3
diso_​to_​phys : 2


Relationships:
none : 80
associated_​with : 2
classifies : 1
isa : 15
location_​of : 1
mapped_​to : 16
may_​prevent : 51
may_​treat : 5
use : 1
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM305img Agent, Cariostatic C0007246
DISO_to_CHEM209img Agent, Cariostatic C0007246
DISO_to_CHEM204img DENT RESTORATION PERMANENT C0011413
DISO_to_DISO192img Complication Aspects C1171258
DISO_to_CHEM172img DENT RESTORATION PERMANENT C0011413
DISO_to_CHEM150img Fluorides C0016327
DISO_to_DISO132img Periodontal Diseases C0031090
DISO_to_ANAT129img Dental Enamel C0011350
DISO_to_ANAT125img Dentin C0011429
DISO_to_CHEM119img Fluorides C0016327
DISO_to_ANAT112img Dentin C0011429
DISO_to_DISO108img Complication Aspects C1171258
DISO_to_ANAT107img Deciduous tooth C3266841
DISO_to_ANAT102img Saliva C0036087
DISO_to_CHEM100img DENT SEALANTS C0031992
DISO_to_DISO89img Dental Plaque C0011389
DISO_to_DISO89img Periodontal Diseases C0031090
DISO_to_ANAT85img Deciduous tooth C3266841
DISO_to_CHEM83img Composite Resins C0009570
DISO_to_CHEM81img Fluorides, Topical C0016328
DISO_to_ANAT77img Dental Enamel C0011350
DISO_to_CHEM72img DENT SEALANTS C0031992
DISO_to_PHYS71img Dental Caries Susceptibility C0011336
DISO_to_ANAT70img Molar C0026367
DISO_to_ANAT62img Saliva C0036087
Genes (34)

Species:
human : 34
Page Size
Current 25
  Page 1 of 2
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanFERMT155612fermitin family member 1
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanNOP1055505NOP10 ribonucleoprotein
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanOSTM128962osteopetrosis associated transmembrane protein 1
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTINF226277TERF1 (TRF1)-interacting nuclear factor 2
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanATP6V0A223545ATPase, H+ transporting, lysosomal V0 subunit a2
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanSEC23A10484Sec23 homolog A (S. cerevisiae)
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTCIRG110312T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTP638626tumor protein p63
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTNFSF118600tumor necrosis factor (ligand) superfamily, member 11
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanAP3B18546adaptor-related protein complex 3, beta 1 subunit
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanOFD18481oral-facial-digital syndrome 1
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanVDR7421vitamin D (1,25- dihydroxyvitamin D3) receptor
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTRPS17227trichorhinophalangeal syndrome I
img OMIM, Score=882, UMLKSK CUI: C0011334
HumanTGFB17040transforming growth factor, beta 1
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTERT7015telomerase reverse transcriptase
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTERC7012telomerase RNA component
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanTBCE6905tubulin folding cofactor E
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanLAMC23918laminin, gamma 2
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanLAMB33914laminin, beta 3
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanLAMA33909laminin, alpha 3
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanKRT143861keratin 14
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanITGB43691integrin, beta 4
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanGJA12697gap junction protein, alpha 1, 43kDa
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanFGFR22263fibroblast growth factor receptor 2
img OMIM, Score=1000, UMLKSK CUI: C0011334
HumanFGFR32261fibroblast growth factor receptor 3
img OMIM, Score=1000, UMLKSK CUI: C0011334
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0011334Dental Caries0self