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Details
Link-It Detail - Disease - Dementia, Vascular
Debug Stats
  • ### Total Build Time: 34 ms 48.967 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 334 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 335 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 1.830 KB
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 986 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=7 ms Completed: 7 ms rowSize= 10.523 KB
  • CONCEPT_RELATIONSHIPS gt=9 ms Completed: 9 ms rowSize= 12.932 KB
  • CONCEPT_GENES gt=10 ms Completed: 10 ms rowSize= 20.702 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.152 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Dementia, Vascular C0011269
Definition (1)
A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (4)
img Leukoencephalopathies C0270612
img Intracranial Arteriosclerosis C0007771
img Cerebrovascular Disorders C0007820
img Dementia C0497327
Children (2)
img CADASIL C0751587
img Dementia, Multi-Infarct C0011263
Ancestral Roots
RootRoot Plus OneDepthParent
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076824img Leukoencephalopathies C0270612
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Leukoencephalopathies C0270612
img Cardiovascular Diseases C0007222img Vascular Diseases C00423736img Intracranial Arteriosclerosis C0007771
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076827img Intracranial Arteriosclerosis C0007771
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Cerebrovascular Disorders C0007820
img Cardiovascular Diseases C0007222img Vascular Diseases C00423734img Cerebrovascular Disorders C0007820
img Mental Disorders C0004936img Delirium, Dementia, Amnestic, Cognitive Disorders C00292274img Dementia C0497327
img Nervous System Diseases C0027765img Central Nervous System Diseases C00076825img Dementia C0497327
Relationships (74)

Relation Types:
diso_​to_​anat : 12
diso_​to_​chem : 15
diso_​to_​diso : 37
diso_​to_​phen : 2
diso_​to_​phys : 8


Relationships:
none : 64
is_​associated_​anatomic_​site_​of : 2
isa : 7
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO355img Alzheimer Disease C0002395
DISO_to_DISO267img Alzheimer Disease C0002395
DISO_to_DISO140img Cognition Disorders C0009241
DISO_to_DISO103img Cognition Disorders C0009241
DISO_to_DISO103img Complication Aspects C1171258
DISO_to_DISO89img Complication Aspects C1171258
DISO_to_ANAT88img Brain C0006104
DISO_to_PHEN85img genetic aspects C0017399
DISO_to_ANAT82img Brain C0006104
DISO_to_PHEN58img genetic aspects C0017399
DISO_to_CHEM54img Cholinesterase Inhibitors C0008425
DISO_to_DISO39img Cerebrovascular accident C0038454
DISO_to_ANAT38img In Blood C0005768
DISO_to_DISO37img Cerebrovascular accident C0038454
DISO_to_ANAT36img In Blood C0005768
DISO_to_DISO35img Dementia C0497327
DISO_to_PHYS32img Cognition C0009240
DISO_to_DISO27img Cerebrovascular Disorders C0007820
DISO_to_PHYS27img Aging C0001811
DISO_to_CHEM26img Agents, Nootropic C0242913
DISO_to_DISO25img Brain Ischemia C0007786
DISO_to_CHEM24img 6H-Benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl- C0016967
DISO_to_DISO24img Dementia C0497327
DISO_to_PHYS24img Cerebrovascular Circulation C0007818
DISO_to_DISO23img Cerebral Infarction C0007785
Genes (17)

Species:
human : 17
SpeciesGeneGeneIdGene NameEvidence
HumanTNFSF148740tumor necrosis factor (ligand) superfamily, member 14
img GENERIF, Score=1000, Pubmed Id: 18320356, UMLKSK CUI: C0011269
HumanVEGFA7422vascular endothelial growth factor A
img GENERIF, Score=1000, Pubmed Id: 16583410, UMLKSK CUI: C0011269
HumanTGFB17040transforming growth factor, beta 1
img GENERIF, Score=1000, Pubmed Id: 16990569, UMLKSK CUI: C0011269
img GENERIF, Score=913, Pubmed Id: 16904244, UMLKSK CUI: C0011269
HumanSREBF26721sterol regulatory element binding transcription factor 2
img GENERIF, Score=1000, Pubmed Id: 16082694, UMLKSK CUI: C0011269
HumanPRNP5621prion protein
img GENERIF, Score=694, Pubmed Id: 17570906, UMLKSK CUI: C0011269
HumanPON15444paraoxonase 1
img GENERIF, Score=1000, Pubmed Id: 12480737, UMLKSK CUI: C0011269
HumanPLA2G2A5320phospholipase A2, group IIA (platelets, synovial fluid)
img GENERIF, Score=1000, Pubmed Id: 17447002, UMLKSK CUI: C0011269
HumanNOTCH34854notch 3
INFERRED, Score=800, UMLKSK CUI: C0011269
HumanICAM13383intercellular adhesion molecule 1
img GAD, Score=1000, Pubmed Id: 12095649, UMLKSK CUI: C0011269
HumanCST31471cystatin C
img GENERIF, Score=694, Pubmed Id: 14672279, UMLKSK CUI: C0011269
HumanCRP1401C-reactive protein, pentraxin-related
img GENERIF, Score=1000, Pubmed Id: 18841009, UMLKSK CUI: C0011269
HumanC5AR1728complement component 5a receptor 1
img GENERIF, Score=734, Pubmed Id: 12759460, UMLKSK CUI: C0011269
HumanAVP551arginine vasopressin
img GENERIF, Score=1000, Pubmed Id: 15624761, UMLKSK CUI: C0011269
HumanAPOE348apolipoprotein E
img GENERIF, Score=1000, Pubmed Id: 14739533, UMLKSK CUI: C0011269
img GENERIF, Score=1000, Pubmed Id: 15375590, UMLKSK CUI: C0011269
img GENERIF, Score=1000, Pubmed Id: 16758323, UMLKSK CUI: C0011269
img GENERIF, Score=1000, Pubmed Id: 12417379, UMLKSK CUI: C0011269
HumanAGT183angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
img GENERIF, Score=1000, Pubmed Id: 16603315, UMLKSK CUI: C0011269
HumanJAG1182jagged 1
INFERRED, Score=800, UMLKSK CUI: C0011269
HumanAGER177advanced glycosylation end product-specific receptor
img GENERIF, Score=1000, Pubmed Id: 16286548, UMLKSK CUI: C0011269
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0011269Dementia, Vascular0self