Human | FAM20C | 56975 | family with sequence similarity 20, member C | |
Human | VEGFA | 7422 | vascular endothelial growth factor A | The angiogenic growth factor VEGF-A is strongly expressed in hyperplastic epithelium overlying granulation tissue in airway stenosis An intense expression of VEGF and MMP-9 in carotid plaques is related to plaque instability, high degree of stenosis and presence of symptomatic carotid occlusive disease |
Human | VDR | 7421 | vitamin D (1,25- dihydroxyvitamin D3) receptor | Title:|Association:Y|Conclusion:There is a significant association of vitamin D receptor polymorphism with calcific aortic valve stenosis. The B allele of the vitamin D receptor is more common in patients with calcific aortic valve stenosis. It now needs to be evaluated whether other genes that control calcium homeostasis are involved in the pathogenesis of this disorder. |
Human | TLR4 | 7099 | toll-like receptor 4 | Suggest that TLR2/4 may play role in aortic valve inflammation and stenosis |
Human | TBCE | 6905 | tubulin folding cofactor E | Medullary stenosis of tubular bones |
Human | CCL5 | 6352 | chemokine (C-C motif) ligand 5 | The frequency of the RANTES-403G allele was significantly higher in patients with stenosis >70% (OR, 2.45; 95% CI 1.12-5.71; p=0.015) |
Human | PTPN11 | 5781 | protein tyrosine phosphatase, non-receptor type 11 | The most prevalent links to PTPN11 gene dysfunction in cardiac development in patients with a PTPN11 mutation are pulmonary valve stenosis, atrial septal defect, ostium secundum type, and stenosis of the peripheral pulmonary arteries |
Human | PECAM1 | 5175 | platelet/endothelial cell adhesion molecule 1 | platelet endothelial cell adhesion molecule-1 (PECAM-1) gene is responsive to shear stress in vitro and that decreased PECAM-1 gene expression in 53A carriers may influence reduced progression of vessel stenosis in patients with coronary artery disease |
Human | NPPB | 4879 | natriuretic peptide B | Basal BNP level testing can be recommended in the follow-up evaluation percutaneous coronary intervention, to improve both the detection and the exclusion of asymptomatic re-stenosis |
Human | NOS3 | 4846 | nitric oxide synthase 3 (endothelial cell) | Title:Endothelial nitric oxide synthase gene is associated with vessel stenosis in Korean population.|Association:Y|Conclusion:Our data suggest that eNOS gene polymorphisms may play an important role in the pathogenesis of vessel stenosis in Korean population. |
Human | MEF2A | 4205 | myocyte enhancer factor 2A | Coronary angiogram showing greater than 70% stenosis |
Human | ITGB4 | 3691 | integrin, beta 4 | Ureterovesical junction stenosis |
Human | ITGAL | 3683 | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | Increased expression or CD11A may affect the development of initial atherosclerotic coronary stenosis, but not re-stenosis |
Human | ITGA6 | 3655 | integrin, alpha 6 | Ureterovesical junction stenosis |
Human | ICAM1 | 3383 | intercellular adhesion molecule 1 | Increased expression of ICAM1 may affect the development of initial atherosclerotic coronary stenosis, but not re-stenosis |
Human | HOXA2 | 3199 | homeobox A2 | Near-stenosis of bony portion of auditory canal |
Human | FGFR2 | 2263 | fibroblast growth factor receptor 2 | Jugular foraminal stenosis Choanal atresia or stenosis |
Human | FGFR1 | 2260 | fibroblast growth factor receptor 1 | Choanal atresia or stenosis |
Human | FGB | 2244 | fibrinogen beta chain | frequencies of the beta-fibrinogen 448 A allele were higher in patients with no flow-limiting stenosis after myocardial infarction |
Human | F2 | 2147 | coagulation factor II (thrombin) | Increasing plaque echogenicity and the degree of stenosis is associated with thrombin generation in persons with carotid stenosis |
Human | EYA1 | 2138 | eyes absent homolog 1 (Drosophila) | Lacrimal duct aplasia or stenosis (25% of patients) |
Human | CRP | 1401 | C-reactive protein, pentraxin-related | High-sensitivity CRP is correlated with neurologic symptoms and plaque instability in patients with severe stenosis of the carotid bifurcation The magnitude of the systemic inflammatory response triggered by coronary angioplasty assessed as an increase in CRP level and the history of coronary angioplasty concerning nontarget stenosis remain independent predictors of lesion re-narrowing |
Human | APOE | 348 | apolipoprotein E | carotid ultrasound results (intimal-medial thickness and stenosis) were related to three APOE genotypes |