Human | ZNF469 | 84627 | zinc finger protein 469 | |
Human | FBRS | 64319 | fibrosin | In a mouse model, fibrosin upregulates the appearance of myofibroblasts during wound healing and may be important in the process of scarring |
Human | SMARCAL1 | 50485 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 | |
Human | TNFSF12 | 8742 | tumor necrosis factor (ligand) superfamily, member 12 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | IKBKG | 8517 | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | STAGE 4 - skin pallor, atrophy, and scarring |
Human | VEGFA | 7422 | vascular endothelial growth factor A | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | UROS | 7390 | uroporphyrinogen III synthase | |
Human | TP73 | 7161 | tumor protein p73 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | TP53 | 7157 | tumor protein p53 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | TNXB | 7148 | tenascin XB | |
Human | TGFBR3 | 7049 | transforming growth factor, beta receptor III | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | TGFBR2 | 7048 | transforming growth factor, beta receptor II (70/80kDa) | Filtering bleb scarring is associated with an abundant expression of TGF-beta receptors in activated fibroblasts and the deposition of the fibrogenic ED-A fibronectin splice-variant |
Human | TGFBR1 | 7046 | transforming growth factor, beta receptor 1 | TGFbeta1/ALK5 may alleviate scarring in chronic fibrotic disease |
Human | TGFB3 | 7043 | transforming growth factor, beta 3 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | TGFB1I1 | 7041 | transforming growth factor beta 1 induced transcript 1 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | TGFB1 | 7040 | transforming growth factor, beta 1 | the expression of TGF-beta 1, and proliferation of myofibroblasts within the valves have a potential role in the valvular fibrosis, calcification, and changes in the extracellular matrix that lead to the scarring sequelae of rheumatic heart disease |
Human | STAT3 | 6774 | signal transducer and activator of transcription 3 (acute-phase response factor) | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | SP1 | 6667 | Sp1 transcription factor | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | PLEC | 5339 | plectin | Minimal or absent scarring |
Human | PIK3CA | 5290 | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | PCNA | 5111 | proliferating cell nuclear antigen | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | SERPINE1 | 5054 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | MMP9 | 4318 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | A coding SNP (Q279R in exon 6) within the MMP9 gene to be associated with a lowered risk of trachomatous scarring and trichiasis |
Human | SMAD7 | 4092 | SMAD family member 7 | INFERRED, Score=800, UMLKSK CUI: C0008767 |
Human | SMAD6 | 4091 | SMAD family member 6 | INFERRED, Score=800, UMLKSK CUI: C0008767 |