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Genes (156)
Species: human : 156 | |
Human | GGT2 | 728441 | gamma-glutamyltransferase 2 | Transitional cell carcinomas (TCC) in both rat and Man were characterized by decreased alkaline phosphatase (ALP) and increased gamma-glutamyl transpeptidase (GGT), beta-glucuronidase (beta-G1), succinate dehydrogenase (SD) and glucose-6-phosphate dehydrogenase (G6PD) activities. | Human | FLCN | 201163 | folliculin | Associated endometrial carcinoma, atypical endometrial hyperplasia, uterine leiomyosarcoma, bladder transitional carcinoma, gastric, biliary and renal cell carcinoma | Human | CKS1A | 137529 | | Results suggest that CKS1 has a supporting role for SKP2 (S-phase kinase-associated protein 2) function in human urothelial carcinoma | Human | KISS1R | 84634 | KISS1 receptor | Metastin (KISS-1) and metastin-coupled receptor (GPR54) expression in transitional cell carcinoma of the bladder. | Human | CD276 | 80381 | CD276 molecule | B7-H3 is highly expressed in urothelial cell carcinoma across tumor stages, whereas B7-H1 and PD-1 expression are associated with advanced disease | Human | CTNNBIP1 | 56998 | catenin, beta interacting protein 1 | adenomatous polyposis coli gene and nuclear b-catenin may have roles in wnt-related progression of invasive urothelial carcinomas | Human | KRT20 | 54474 | keratin 20 | Overexpressed in recurrent superficial urothelial carcinoma | Human | RRM2B | 50484 | ribonucleotide reductase M2 B (TP53 inducible) | Genomic DNA from 108 primary transitional cell carcinomas (TCCs; 81 of the urinary bladder and 27 of the renal pelvis or ureter) was analyzed for mutation in the p53R2 gene by direct sequencing. Infrequent alteration in the p53R2 gene in human transitional cell carcinoma of the urinary tract. | Human | CTAG2 | 30848 | cancer/testis antigen 2 | The frequency of expression in transitional cell carcinomas (TCCs) of NY-ESO-1, the most immunogenic CT antigen to date, and its closely related gene LAGE-1 was studied. | Human | UBIAD1 | 29914 | UbiA prenyltransferase domain containing 1 | Isolation and characterization of the TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder. | Human | CD274 | 29126 | CD274 molecule | B7-H3 is highly expressed in urothelial cell carcinoma across tumor stages, whereas B7-H1 and PD-1 expression are associated with advanced disease | Human | MLH3 | 27030 | mutL homolog 3 (E. coli) | Associated endometrial carcinoma, atypical endometrial hyperplasia, uterine leiomyosarcoma, bladder transitional carcinoma, gastric, biliary and renal cell carcinoma | Human | TREH | 11181 | trehalase (brush-border membrane glycoprotein) | AIM: To study the effect of tretinoin (Tre) or retinol (Ret) on the proliferation of lymphokine-activated killer (LAK) cells in patients with transitional cell cancer of bladder and their cytolysis to bladder tumor cells. | Human | IRF9 | 10379 | interferon regulatory factor 9 | Impaired alpha-interferon signaling in transitional cell carcinoma: lack of p48 expression in 5637 cells. | Human | MSLN | 10232 | mesothelin | The carcinomas that most frequently exhibited strong mesothelin reactivity were nonmucinous carcinomas of the ovary (14 of 14 serous, 3 of 3 endometrioid, 6 of 8 clear cell, and 4 of 4 transitional cell carcinoma), and adenocarcinomas of the pancreas (12 of 14), the ampulla of Vater (3 of 3), endometrium (7 of 11), lung (14 of 34), and liver (7 of 19 cholangiocarcinomas). | Human | MVP | 9961 | major vault protein | The LRP mRNA level was significantly greater in normal bladder tissue than in transitional cell carcinoma bladder tissue (P <0.01) and in superficial cancer than in invasive cancer (P = 0.013). | Human | DLGAP5 | 9787 | discs, large (Drosophila) homolog-associated protein 5 | OBJECTIVES: To assess the expression rate of a cancer-related gene, hepatoma-up-regulated protein (HURP), in the tumor tissue of transitional cell carcinoma (TCC), and to assess the potential suitability of using this gene as a novel molecular marker for detecting TCC in voided urine. We recently found a urinary molecular marker, Hepatoma-Up-Regulated Protein (HURP), for the detection of urinary bladder transitional cell carcinoma (TCC). | Human | PTGES | 9536 | prostaglandin E synthase | We aimed to characterize cPLA(2), cyclooxygenase 2 (COX2) and prostaglandine E synthase (PGES) expression in human transitional carcinoma (TCC) of the urinary bladder and correlate with the Ki-67 proliferating marker. | Human | CLDN1 | 9076 | claudin 1 | claudins 1 and 3 had a significant effect on overall survival in patients with urothelial carcinoma of the upper urinary tract | Human | CFLAR | 8837 | CASP8 and FADD-like apoptosis regulator | The frequent expression and coexpression of Fas, FasL, and c-FLIP in urothelial carcinomas implicates c-FLIP as an inhibitor of the Fas-FasL-induced death pathway in these tumors | Human | PDE5A | 8654 | phosphodiesterase 5A, cGMP-specific | Immunohistochemistry showed that PDE5 was overexpressed in human squamous and transitional cell carcinomas compared with normal urothelium. | Human | TP63 | 8626 | tumor protein p63 | Click here to display 10 evidence detail records. | Human | LY6D | 8581 | lymphocyte antigen 6 complex, locus D | CONCLUSIONS: E48 is a sensitive marker for transitional cell carcinoma and suitable for differentiation between urothelial and prostatic undifferentiated carcinoma. AIMS: To investigate the localisation of the E48 epitope and to determine the use of monoclonal antibody E48 for the identification of transitional cell carcinomas (TCC); and to determine if antigenic expression was affected by different standard fixation methods. Use of monoclonal antibody E48 in diagnosing transitional cell carcinoma of urinary bladder. | Human | RECK | 8434 | reversion-inducing-cysteine-rich protein with kazal motifs | In addition, the RECK gene was transfected in the canine transitional cell carcinoma, and its influence on cell proliferation, migration, and invasion was analyzed. | Human | AXIN2 | 8313 | axin 2 | Associated endometrial carcinoma, atypical endometrial hyperplasia, uterine leiomyosarcoma, bladder transitional carcinoma, gastric, biliary and renal cell carcinoma |
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