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Details
Link-It Detail - Disease - Carcinoma, Squamous Cell
Debug Stats
  • ### Total Build Time: 174 ms 57.445 KB
  • CONCEPT_NAME gt=15 ms Completed: 15 ms rowSize= 346 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 705 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=5 ms Completed: 5 ms rowSize= 987 bytes
  • CONCEPT_CHILDREN gt=4 ms Completed: 4 ms rowSize= 552 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.769 KB
  • CONCEPT_RELATIONSHIPS gt=58 ms Completed: 58 ms rowSize= 16.719 KB
  • CONCEPT_GENES gt=91 ms Completed: 91 ms rowSize= 34.061 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.158 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Carcinoma, Squamous Cell C0007137
Definition (1)
A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma.
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Neoplasms, Squamous Cell C0206720
img Carcinoma C0007097
Children (1)
img Bowens Disease C0006079
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Neoplasms, Squamous Cell C0206720
img Neoplasms C0027651img Neoplasms by Histologic Type C00276525img Carcinoma C0007097
Relationships (448)

Relation Types:
diso_​to_​anat : 39
diso_​to_​chem : 134
diso_​to_​diso : 230
diso_​to_​gene : 14
diso_​to_​phen : 4
diso_​to_​phys : 27


Relationships:
none : 346
disease_​has_​associated_​disease : 1
eo_​disease_​maps_​to_​human_​disease : 13
gene_​associated_​with_​disease : 8
gene_​product_​malfunction_​associated_​with_​disease : 1
is_​abnormal_​cell_​of_​disease : 5
is_​finding_​of_​disease : 2
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 3
is_​not_​finding_​of_​disease : 1
isa : 60
mapped_​to : 1
may_​treat : 3
permuted_​term_​of : 1
use : 1
Page Size
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  Page 1 of 18
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO2972img Head and Neck Neoplasms C0018671
DISO_to_PHEN2734img genetic aspects C0017399
DISO_to_DISO2345img Mouth Neoplasms C0026640
DISO_to_DISO2180img Esophageal Neoplasms C0014859
DISO_to_DISO2100img Head and Neck Neoplasms C0018671
DISO_to_PHEN1879img genetic aspects C0017399
DISO_to_DISO1547img Esophageal Neoplasms C0014859
DISO_to_DISO1535img Mouth Neoplasms C0026640
DISO_to_DISO1524img Cutaneous tumor C0037286
DISO_to_DISO1329img Adenocarcinoma C0001418
DISO_to_DISO1156img Lung Neoplasms C0024121
DISO_to_DISO1148img Uterine Cervical Neoplasm C0007873
DISO_to_DISO1035img Cutaneous tumor C0037286
DISO_to_DISO1030img Uterine Cervical Neoplasm C0007873
DISO_to_DISO975img Laryngeal Neoplasms C0023055
DISO_to_CHEM962img BIOCHEM TUMOR MARKERS C0041366
DISO_to_DISO948img Laryngeal Neoplasms C0023055
DISO_to_DISO872img Adenocarcinoma C0001418
DISO_to_DISO778img Lung Neoplasms C0024121
DISO_to_DISO651img LOCAL NEOPL RECURRENCE C0027643
DISO_to_CHEM626img Antineoplastic Agents C0003392
DISO_to_DISO601img Complication Aspects C1171258
DISO_to_DISO586img Disease due to Papilloma virus C0950124
DISO_to_DISO549img NEOPL TONGUE C0040411
DISO_to_CHEM514img BIOCHEM TUMOR MARKERS C0041366
Genes (668)

Species:
human : 646
mouse : 22
Page Size
Current 25
  Page 1 of 27
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
MouseFETUB26998fetuin B
img NCI, Score=801, Pubmed Id: 15499407, UMLKSK CUI: C0007137
MouseTRIM3222954tripartite motif containing 32
img NCI, Score=801, Pubmed Id: 14578165, UMLKSK CUI: C0007137
MouseLY6D8581lymphocyte antigen 6 complex, locus D
Click here to display 4 evidence detail records.
MouseHMGA28091high mobility group AT-hook 2
img NCI, Score=801, Pubmed Id: 17305714, UMLKSK CUI: C0007137
MouseTFPI27980tissue factor pathway inhibitor 2
img NCI, Score=801, Pubmed Id: 16144329, UMLKSK CUI: C0007137
MouseXPC7508xeroderma pigmentosum, complementation group C
Click here to display 3 evidence detail records.
MouseTCF7L26934transcription factor 7-like 2 (T-cell specific, HMG-box)
img NCI, Score=801, Pubmed Id: 15765534, UMLKSK CUI: C0007137
MouseTCF46925transcription factor 4
img NCI, Score=801, Pubmed Id: 15765534, UMLKSK CUI: C0007137
MouseST146768suppression of tumorigenicity 14 (colon carcinoma)
img NCI, Score=801, Pubmed Id: 16103220, UMLKSK CUI: C0007137
MousePVRL15818poliovirus receptor-related 1 (herpesvirus entry mediator C)
img NCI, Score=801, Pubmed Id: 16000587, UMLKSK CUI: C0007137
MouseSMAD74092SMAD family member 7
img NCI, Score=801, Pubmed Id: 14633701, UMLKSK CUI: C0007137
MouseSMAD64091SMAD family member 6
img NCI, Score=801, Pubmed Id: 14633701, UMLKSK CUI: C0007137
MouseKRT133860keratin 13
img NCI, Score=801, Pubmed Id: 1711471, UMLKSK CUI: C0007137
MouseJUN3725jun proto-oncogene
img NCI, Score=801, Pubmed Id: 14517347, UMLKSK CUI: C0007137
MouseDNAJB13337DnaJ (Hsp40) homolog, subfamily B, member 1
Click here to display 4 evidence detail records.
MouseHIF1A3091hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
img NCI, Score=801, Pubmed Id: 11085544, UMLKSK CUI: C0007137
MouseCXCL12919chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
img NCI, Score=801, Pubmed Id: 11745457, UMLKSK CUI: C0007137
img NCI, Score=801, Pubmed Id: 11745457, UMLKSK CUI: C0007137
MouseFYN2534FYN oncogene related to SRC, FGR, YES
img NCI, Score=801, Pubmed Id: 11684709, UMLKSK CUI: C0007137
MouseERCC62074excision repair cross-complementing rodent repair deficiency, complementation group 6
Click here to display 3 evidence detail records.
MouseCDH1999cadherin 1, type 1, E-cadherin (epithelial)
img NCI, Score=801, Pubmed Id: 1316085, UMLKSK CUI: C0007137
MouseCD81975CD81 molecule
img NCI, Score=801, Pubmed Id: 11431366, UMLKSK CUI: C0007137
MouseCD80941CD80 molecule
img NCI, Score=801, Pubmed Id: 11122458, UMLKSK CUI: C0007137
HumanLOC100507436100507436
Click here to display 3 evidence detail records.
HumanGGT2728441gamma-glutamyltransferase 2
Click here to display 11 evidence detail records.
HumanMAGED4728239melanoma antigen family D, 4
img NCI, Score=801, Pubmed Id: 16225959, UMLKSK CUI: C0007137
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0007137Carcinoma, Squamous Cell0self