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Details
Link-It Detail - Disease - Carcinoid Tumor
Debug Stats
  • ### Total Build Time: 196 ms 65.570 KB
  • CONCEPT_NAME gt=11 ms Completed: 11 ms rowSize= 328 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 687 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 989 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 566 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.771 KB
  • CONCEPT_RELATIONSHIPS gt=125 ms Completed: 125 ms rowSize= 14.833 KB
  • CONCEPT_GENES gt=54 ms Completed: 54 ms rowSize= 44.098 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.149 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Carcinoid Tumor C0007095
Definition (1)
A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
Semantic Types (1)
Neoplastic Process (T191)
Parents (2)
img Neuroendocrine Tumors C0206754
img Adenocarcinoma C0001418
Children (1)
img Malignant Carcinoid Syndrome C0024586
Ancestral Roots
RootRoot Plus OneDepthParent
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Neuroendocrine Tumors C0206754
img Neoplasms C0027651img Neoplasms by Histologic Type C00276526img Adenocarcinoma C0001418
Relationships (109)

Relation Types:
diso_​to_​anat : 15
diso_​to_​chem : 10
diso_​to_​diso : 81
diso_​to_​phen : 3


Relationships:
none : 71
eo_​disease_​maps_​to_​human_​disease : 2
is_​abnormal_​cell_​of_​disease : 5
is_​finding_​of_​disease : 3
is_​normal_​cell_​origin_​of_​disease : 1
is_​normal_​tissue_​origin_​of_​disease : 1
is_​not_​abnormal_​cell_​of_​disease : 1
is_​primary_​anatomic_​site_​of_​disease : 1
isa : 22
may_​be_​finding_​of_​disease : 1
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 5
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO186img Complication Aspects C1171258
DISO_to_DISO166img Lung Neoplasms C0024121
DISO_to_DISO161img Complication Aspects C1171258
DISO_to_DISO130img Lung Neoplasms C0024121
DISO_to_DISO104img Stomach Neoplasms C0038356
DISO_to_DISO98img Bronchial Neoplasms C0006264
DISO_to_DISO95img Stomach Neoplasms C0038356
DISO_to_DISO91img BRONCHIAL NEOPL C0006264
DISO_to_DISO88img Rectal Neoplasms C0034885
DISO_to_DISO87img Liver Neoplasms C0023903
DISO_to_DISO82img APPENDICEAL NEOPL C0003614
DISO_to_DISO82img Liver Neoplasms C0023903
DISO_to_DISO75img Gastrointestinal Neoplasms C0017185
DISO_to_DISO67img ILEAL NEOPL C0020876
DISO_to_DISO62img Gastrointestinal Neoplasms C0017185
DISO_to_DISO60img Intestinal Neoplasms C0021841
DISO_to_DISO56img APPENDICEAL NEOPL C0003614
DISO_to_DISO56img MULTIPLE PRIMARY NEOPL C0027663
DISO_to_DISO56img Pancreatic Neoplasm C0030297
DISO_to_DISO55img INTESTINAL NEOPL C0021841
DISO_to_DISO55img Rectal Neoplasms C0034885
DISO_to_PHEN52img genetic aspects C0017399
DISO_to_DISO50img ILEAL NEOPL C0020876
DISO_to_DISO47img Adenocarcinoma C0001418
DISO_to_DISO46img Adenocarcinoma C0001418
Genes (81)

Species:
human : 81
Page Size
Current 25
  Page 1 of 4
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanTMEM30B161291transmembrane protein 30B
img NCI, Score=801, Pubmed Id: 15375526, UMLKSK CUI: C0007095
HumanREG483998regenerating islet-derived family, member 4
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 16086444, UMLKSK CUI: C0007095
HumanPTCHD257540patched domain containing 2
img NCI, Score=801, Pubmed Id: 15645143, UMLKSK CUI: C0007095
HumanTSG1150970Tumor suppressor gene on chromosome 11
img NCI, Score=801, Pubmed Id: 8784062, UMLKSK CUI: C0007095
HumanPDCD427250programmed cell death 4 (neoplastic transformation inhibitor)
img GENERIF, Score=694, Pubmed Id: 15153438, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 15153438, UMLKSK CUI: C0007095
HumanPRKD225865protein kinase D2
img GENERIF, Score=734, Pubmed Id: 16899224, UMLKSK CUI: C0007095
HumanIGF2BP310643insulin-like growth factor 2 mRNA binding protein 3
img GENERIF, Score=1000, Pubmed Id: 17521698, UMLKSK CUI: C0007095
img GENERIF, Score=827, Pubmed Id: 17316760, UMLKSK CUI: C0007095
HumanSCGN10590secretagogin, EF-hand calcium binding protein
img NCI, Score=801, Pubmed Id: 16955307, UMLKSK CUI: C0007095
HumanMSLN10232mesothelin
img NCI, Score=801, Pubmed Id: 14576474, UMLKSK CUI: C0007095
HumanCLDN19076claudin 1
img GENERIF, Score=1000, Pubmed Id: 17418912, UMLKSK CUI: C0007095
HumanNRP28828neuropilin 2
img NCI, Score=801, Pubmed Id: 11394892, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 11394892, UMLKSK CUI: C0007095
HumanSCG27857secretogranin II
img NCI, Score=801, Pubmed Id: 7891024, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 2447696, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 7891024, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 7515371, UMLKSK CUI: C0007095
HumanWT17490Wilms tumor 1
img GENERIF, Score=1000, Pubmed Id: 17721194, UMLKSK CUI: C0007095
HumanTPH17166tryptophan hydroxylase 1
Click here to display 14 evidence detail records.
HumanNKX2-17080
img NCI, Score=801, Pubmed Id: 11957142, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 11679943, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 11679943, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 11679943, UMLKSK CUI: C0007095
img GENERIF, Score=1000, Pubmed Id: 11957142, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 11790979, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 10757334, UMLKSK CUI: C0007095
HumanTGFB37043transforming growth factor, beta 3
img NCI, Score=801, Pubmed Id: 9255608, UMLKSK CUI: C0007095
HumanTGFB27042transforming growth factor, beta 2
img NCI, Score=801, Pubmed Id: 9255608, UMLKSK CUI: C0007095
HumanTFF17031trefoil factor 1
img NCI, Score=801, Pubmed Id: 9221803, UMLKSK CUI: C0007095
HumanTERT7015telomerase reverse transcriptase
img GENERIF, Score=861, Pubmed Id: 15837730, UMLKSK CUI: C0007095
HumanTERC7012telomerase RNA component
img NCI, Score=801, Pubmed Id: 10426823, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 9192812, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 11720437, UMLKSK CUI: C0007095
HumanSYP6855synaptophysin
Click here to display 29 evidence detail records.
HumanSTAT26773signal transducer and activator of transcription 2, 113kDa
img NCI, Score=801, Pubmed Id: 11408801, UMLKSK CUI: C0007095
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
img NCI, Score=801, Pubmed Id: 11408801, UMLKSK CUI: C0007095
HumanSSTR16751somatostatin receptor 1
img NCI, Score=801, Pubmed Id: 15801004, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 8132773, UMLKSK CUI: C0007095
img NCI, Score=801, Pubmed Id: 8653698, UMLKSK CUI: C0007095
HumanSSR26746signal sequence receptor, beta (translocon-associated protein beta)
img NCI, Score=801, Pubmed Id: 9170433, UMLKSK CUI: C0007095
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0007095Carcinoid Tumor0self