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Details
Link-It Detail - Disease - Bronchopulmonary Dysplasia
Debug Stats
  • ### Total Build Time: 170 ms 44.063 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 350 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 591 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=14 ms Completed: 14 ms rowSize= 1,011 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=38 ms Completed: 38 ms rowSize= 4.124 KB
  • CONCEPT_RELATIONSHIPS gt=85 ms Completed: 85 ms rowSize= 12.907 KB
  • CONCEPT_GENES gt=23 ms Completed: 23 ms rowSize= 23.747 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.160 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Bronchopulmonary Dysplasia C0006287
Definition (1)
A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Infant, Premature, Diseases C0021295
img Ventilator-Induced Lung Injury C2350350
Ancestral Roots
RootRoot Plus OneDepthParent
img Congenital, Hereditary, and Neonatal Diseases and Abnormalities C0027612img Infant, Newborn, Diseases C00212904img Infant, Premature, Diseases C0021295
img Respiratory Tract Diseases C0035242img Lung Diseases C00241155img Ventilator-Induced Lung Injury C2350350
img Wounds and Injuries C0043251img Thoracic Injuries C00399805img Ventilator-Induced Lung Injury C2350350
Relationships (71)

Relation Types:
diso_​to_​anat : 10
diso_​to_​chem : 40
diso_​to_​diso : 19
diso_​to_​phen : 2


Relationships:
none : 38
is_​associated_​anatomic_​site_​of : 3
isa : 1
may_​prevent : 28
permuted_​term_​of : 1
Page Size
Current 25
  Page 1 of 3
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO60img Complication Aspects C1171258
DISO_to_DISO56img Infant, Very Low Birth Weight C0282667
DISO_to_ANAT55img Lung C0024109
DISO_to_DISO50img Respiratory Distress Syndrome, Newborn C0035220
DISO_to_DISO45img INFANT PREMATURE DIS C0021295
DISO_to_DISO45img INFANT VLBW C0282667
DISO_to_DISO42img Respiratory Distress Syndrome, Newborn C0035220
DISO_to_PHEN36img genetic aspects C0017399
DISO_to_ANAT34img Lung C0024109
DISO_to_DISO34img Complication Aspects C1171258
DISO_to_DISO29img INFANT PREMATURE DIS C0021295
DISO_to_PHEN26img genetic aspects C0017399
DISO_to_DISO25img HYPEROXIA C0242706
DISO_to_ANAT24img In Blood C0005768
DISO_to_DISO24img Infant, Extremely Low Birth Weight C0456065
DISO_to_CHEM23img GLUCOCORTICOIDS C0017710
DISO_to_CHEM21img Pulmonary Surfactants C0034085
DISO_to_CHEM20img Nitric Oxide C0028128
DISO_to_ANAT19img In Blood C0005768
DISO_to_CHEM19img Dexamethasone C0011777
DISO_to_DISO17img Chorioamnionitis C0008495
DISO_to_ANAT16img Pulmonary Alveoli C0034051
DISO_to_DISO16img Hypertension, Pulmonary C0020542
DISO_to_CHEM15img Anti-Inflammatory Agents C0003209
DISO_to_CHEM15img Dexamethasone C0011777
Genes (19)

Species:
human : 19
SpeciesGeneGeneIdGene NameEvidence
HumanSFTPA1653509surfactant protein A1
img GAD, Score=1000, Pubmed Id: 15102713, UMLKSK CUI: C0006287
HumanTIMP27077TIMP metallopeptidase inhibitor 2
img GENERIF, Score=1000, Pubmed Id: 14973177, UMLKSK CUI: C0006287
HumanTIMP17076TIMP metallopeptidase inhibitor 1
img GENERIF, Score=1000, Pubmed Id: 14973177, UMLKSK CUI: C0006287
img GENERIF, Score=734, Pubmed Id: 12376362, UMLKSK CUI: C0006287
HumanSFTPD6441surfactant protein D
img GAD, Score=1000, Pubmed Id: 15102713, UMLKSK CUI: C0006287
HumanSFTPC6440surfactant protein C
img GAD, Score=1000, Pubmed Id: 15102713, UMLKSK CUI: C0006287
HumanSFTPB6439surfactant protein B
img GAD, Score=1000, Pubmed Id: 15102713, UMLKSK CUI: C0006287
HumanSFTPA2B6436
img GAD, Score=1000, Pubmed Id: 11105614, UMLKSK CUI: C0006287
HumanPRSS25645protease, serine, 2 (trypsin 2)
img GENERIF, Score=1000, Pubmed Id: 12949286, UMLKSK CUI: C0006287
HumanMMP164325matrix metallopeptidase 16 (membrane-inserted)
img GENERIF, Score=1000, Pubmed Id: 18784838, UMLKSK CUI: C0006287
HumanMMP94318matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 14973177, UMLKSK CUI: C0006287
img GENERIF, Score=734, Pubmed Id: 12376362, UMLKSK CUI: C0006287
HumanMMP24313matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
img GENERIF, Score=1000, Pubmed Id: 14973177, UMLKSK CUI: C0006287
img GENERIF, Score=734, Pubmed Id: 12376362, UMLKSK CUI: C0006287
HumanIL103586interleukin 10
img GENERIF, Score=1000, Pubmed Id: 17237722, UMLKSK CUI: C0006287
HumanIL1RN3557interleukin 1 receptor antagonist
img GENERIF, Score=1000, Pubmed Id: 15539764, UMLKSK CUI: C0006287
HumanIL1B3553interleukin 1, beta
img GENERIF, Score=1000, Pubmed Id: 15539764, UMLKSK CUI: C0006287
HumanTNC3371tenascin C
img GENERIF, Score=1000, Pubmed Id: 11850444, UMLKSK CUI: C0006287
HumanGSTA6P2942glutathione S-transferase alpha 6, pseudogene
img GENERIF, Score=1000, Pubmed Id: 14726935, UMLKSK CUI: C0006287
HumanFGF72252fibroblast growth factor 7
img GENERIF, Score=1000, Pubmed Id: 12016100, UMLKSK CUI: C0006287
HumanF2RL12150coagulation factor II (thrombin) receptor-like 1
img GENERIF, Score=1000, Pubmed Id: 15879299, UMLKSK CUI: C0006287
HumanACE1636angiotensin I converting enzyme
img GENERIF, Score=1000, Pubmed Id: 16356438, UMLKSK CUI: C0006287
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0006287Bronchopulmonary Dysplasia0self