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Genes (34)
Species: human : 33 mouse : 1 | |
Mouse | BAMBI | 25805 | BMP and activin membrane-bound inhibitor | Genomic organization and localization of mouse Nma/BAMBI: possible implications related to ameloblastoma formation. | Human | ENAM | 10117 | enamelin | In view of the present results, it is interesting that previous studies have indicated that although ameloblastoma, a non-mineralized odontogenic tumor, transcribes amelogenin mRNA, amelogenin (and enamelin) proteins are not expressed in this tissue. | Human | AIFM1 | 9131 | apoptosis-inducing factor, mitochondrion-associated, 1 | Since no potent apoptosis-inducing factor has been found yet in ameloblastoma, the present study was conducted. | Human | TNFSF11 | 8600 | tumor necrosis factor (ligand) superfamily, member 11 | specimens of ameloblastomas, dentigerous cysts, odontogenic keratocysts, and radicular cysts were subjected to immunohistochemical analysis for RANKL and tartrate-resistant acid phosphatase (TRAP) RESULTS: Expression of PTHrP, ODF/RANKL, and OCIF/OPG mRNA was detected in all tooth germ and ameloblastoma samples. | Human | VCAM1 | 7412 | vascular cell adhesion molecule 1 | [Expression of ICAM-1 and VCAM-1 in human ameloblastoma and odontogenic keratocyst] OBJECTIVE: To study the expression of ICAM-1 and VCAM-1 in human ameloblastoma (AB) and odontogenic keratocyst (OKC) and investigate the relation of ICAM-1 and VCAM-1 with the pathologic characteristic of AB and OKC. | Human | TNFRSF1B | 7133 | tumor necrosis factor receptor superfamily, member 1B | In the present study, we found that TNFalpha as well as its receptors, TNFR1 (TNF Receptor 1) and TNFR2, were clearly expressed in ameloblastoma tissues and AM-1 cells. | Human | TNFRSF1A | 7132 | tumor necrosis factor receptor superfamily, member 1A | candidate genes that may be involved in the origination of ameloblastoma and several genes previously unidentified in relation to human tooth development | Human | TERC | 7012 | telomerase RNA component | OBJECTIVE: To detect the expression of p53 protein, hTR, and hTERT mRNA in ameloblastoma (AB) and to investigate the clinical biological characteristics of AB. | Human | SMO | 6608 | smoothened, frizzled family receptor | RESULTS: Expression of SHH, PTC, SMO, and GLI1 mRNA was detected in all tooth germ and ameloblastoma samples. | Human | SHH | 6469 | sonic hedgehog | RESULTS: Expression of SHH, PTC, SMO, and GLI1 mRNA was detected in all tooth germ and ameloblastoma samples. signaling molecules might play a role in epithelial-mesenchymal interactions and cell proliferation in tooth development as well as in growth of [ameloblastomas] | Human | SDC2 | 6383 | syndecan 2 | The results indicated that ameloblastoma cells synthesize HSPG and deposit it in their intercellular space. Furthermore, the in-vitro biosynthesis of HSPG core protein by ameloblastoma cells was confirmed using immunofluorescence, immunoprecipitation, and reverse-transcriptase polymerase chain reaction (RT-PCR). | Human | PTEN | 5728 | phosphatase and tensin homolog | Total PTEN was absent in 33.3% of ameloblastomas, while its stabilized, phosphorylated(ser380 / thr382 / thr383) form was absent in 83.3% of tumors | Human | PTCH1 | 5727 | patched 1 | possible relationship between the CGG8 allele in PTCH1 and the risk for ameloblastoma | Human | PDGFRA | 5156 | platelet-derived growth factor receptor, alpha polypeptide | regularly expressed in variable levels in ameloblastomas, and somatic mutations of exon 12 and exon 18 are rare findings | Human | PDGFA | 5154 | platelet-derived growth factor alpha polypeptide | regularly expressed in variable levels in ameloblastomas | Human | TNFRSF11B | 4982 | tumor necrosis factor receptor superfamily, member 11b | RESULTS: Expression of PTHrP, ODF/RANKL, and OCIF/OPG mRNA was detected in all tooth germ and ameloblastoma samples. | Human | NOTCH1 | 4851 | notch 1 | Notch1 intracellular domain positive products were observed in the cells at the peripheral layer of most proliferating epithelial tumor nests in mandibular ameloblastoma | Human | MDK | 4192 | midkine (neurite growth-promoting factor 2) | Midkine (MK) is expressed during tooth development and, since ameloblastoma is thought to be arisen from the epithelium of the odontogenic apparatus or its remnant tissues, the effect of MK in ameloblastoma cell growth should be examined. Midkine induced growth of ameloblastoma through MAPK and Akt pathways. | Human | KRT13 | 3860 | keratin 13 | Cells similar to the stellate reticulum, present in the ameloblastoma and in the ameloblastic fibroma, were positive for CK13, which indicates a nature other than that of the stellate reticulum of the normal dental germ. | Human | KRT4 | 3851 | keratin 4 | Ck 4 mRNA was expressed variably in most odontogenic tumors studied, whereas Ck 1 mRNA was detected in one ameloblastoma only. | Human | KRT1 | 3848 | keratin 1 | Ck 4 mRNA was expressed variably in most odontogenic tumors studied, whereas Ck 1 mRNA was detected in one ameloblastoma only. | Human | ITGB1 | 3688 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | findings suggest an important role of integrin alpha2beta1, alpha3beta1, and alpha5beta1 in the architectural characteristics of ameloblastomas and adenomatoid odentogenic tumor | Human | ITGA5 | 3678 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | findings suggest possible participation of alpha5beta1 integrin in the mechanism of local invasion of ameloblastomas | Human | ITGA3 | 3675 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | findings suggest an important role of integrin alpha2beta1, alpha3beta1, and alpha5beta1 in the architectural characteristics of ameloblastomas and adenomatoid odentogenic tumor | Human | ITGA2 | 3673 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | findings suggest an important role of integrin alpha2beta1, alpha3beta1, and alpha5beta1 in the architectural characteristics of ameloblastomas and adenomatoid odentogenic tumor |
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