Human | PEX26 | 55670 | peroxisomal biogenesis factor 26 | |
Human | ADIPOQ | 9370 | adiponectin, C1Q and collagen domain containing | These results suggest that adiponectin is a key regulator of albuminuria, likely acting through the AMPK pathway to modulate oxidant stress in podocytes |
Human | PEX3 | 8504 | peroxisomal biogenesis factor 3 | |
Human | VEGFA | 7422 | vascular endothelial growth factor A | results suggest that VEGF(165) plays some role in the development of albuminuria in diabetic nephropathy due to type 2 but not type 1 diabetes |
Human | TP53 | 7157 | tumor protein p53 | Title:The p53Pro72Arg polymorphism is associated with albuminuria among aboriginal Australians.|Association:Y|Conclusion:Not Found |
Human | TJP1 | 7082 | tight junction protein 1 | Variants in TJP1 do not appear to be major determinants for albuminuria in the San Antonio Family Diabetes/Gallbladder Study |
Human | SPP1 | 6696 | secreted phosphoprotein 1 | Opn plays an important role in the development of albuminuria, possibly by modulating podocyte signaling and motility |
Human | SELP | 6403 | selectin P (granule membrane protein 140kDa, antigen CD62) | The 290Asn (S290N) variant of P-selectin was associated with a higher prevalence and greater degree of albuminuria in European American siblings of type 2 diabetic families Title:P-selectin gene haplotype associations with albuminuria in the Diabetes Heart Study.|Association:Not Found|Conclusion:The 290Asn (S290N) variant of P-selectin was associated with a higher prevalence and greater degree of albuminuria in European American siblings of type 2 diabetic families. |
Human | CCL5 | 6352 | chemokine (C-C motif) ligand 5 | Genetic variation of CCL5 might be an important risk factor for albuminuria in the non-diabetic Japanese general population |
Human | CCL2 | 6347 | chemokine (C-C motif) ligand 2 | results suggest that monocyte chemoattractant protein-1 is produced in renal tubular cells and released into urine in proportion to the degree of proteinuria (albuminuria), and its increased expression in renal tubuli contributes to renal tubular damage Albuminuria triggers tubular MCP-1/CCL2 expression with subsequent macrophage infiltration |
Human | PEX5 | 5830 | peroxisomal biogenesis factor 5 | |
Human | PEX19 | 5824 | peroxisomal biogenesis factor 19 | |
Human | PEX14 | 5195 | peroxisomal biogenesis factor 14 | |
Human | PEX13 | 5194 | peroxisomal biogenesis factor 13 | |
Human | PEX10 | 5192 | peroxisomal biogenesis factor 10 | |
Human | PEX1 | 5189 | peroxisomal biogenesis factor 1 | |
Human | NPPA | 4878 | natriuretic peptide A | Title:Association between polymorphisms of the atrial natriuretic peptide gene and proteinuria: apopulation-based study.|Association:Y|Conclusion:In the general population of Mexico City, both polymorphisms of ANP are associated with albuminuria independently of hypertension, and could play a role in protecting subjects against development of albuminuria. |
Human | NOS3 | 4846 | nitric oxide synthase 3 (endothelial cell) | The -786C eNOS variant was positively correlated with a higher prevalence and a greater degree of albuminuria in European American families in both diabetic and nondiabetic family members The GluAsp or AspAsp genotype of the Glu298Asp polymorphism is significantly associated with ischemic heart disease, but not albuminuria in Japanese diabetic subjects |
Human | GALT | 2592 | galactose-1-phosphate uridylyltransferase | In untreated patients - elevated blood galactose urine reducing substances (galactosuria), hyperchloremic metabolic acidosis, aminoaciduria, elevated liver enzymes, albuminuria |
Human | ACE | 1636 | angiotensin I converting enzyme | Title:Albuminuria and the renin-angiotensin system gene polymorphisms in type-2-diabetic and in normoglycemic hypertensive Chinese|Association:Not Found|Conclusion:In this cohort of Chinese subjects, the ACE gene polymorphism D allele was less frequent in normoglycemic hypertensive patients with albuminuria and in type 2 diabetes. ACE and ADD1 polymorphisms in hypertension have a joint influence on albuminuria |
Human | DCN | 1634 | decorin | The 179 allele variant of the Decorin gene is related to a slower progression of diabetic nephropathy in type 1 diabetic patients with albuminuria and receiving antihypertensive therapy |
Human | AGTR2 | 186 | angiotensin II receptor, type 2 | Title:Albuminuria and the renin-angiotensin system gene polymorphisms in type-2-diabetic and in normoglycemic hypertensive Chinese|Association:Not Found|Conclusion:In this cohort of Chinese subjects, the ACE gene polymorphism D allele was less frequent in normoglycemic hypertensive patients with albuminuria and in type 2 diabetes. |
Human | AGT | 183 | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Title:Albuminuria and the renin-angiotensin system gene polymorphisms in type-2-diabetic and in normoglycemic hypertensive Chinese|Association:Not Found|Conclusion:In this cohort of Chinese subjects, the ACE gene polymorphism D allele was less frequent in normoglycemic hypertensive patients with albuminuria and in type 2 diabetes. Title:Angiotensinogen T235 and ACE insertion/deletion polymorphisms associated with albuminuria in Chinese type 2 diabetic patients.|Association:Y|Conclusion:The high frequencies of the TT genotype and T allele in Chinese populations may contribute to the high prevalence of albuminuria in patients with type 2 diabetes. The possibility of synergism between the AGT TT genotype and the ACE D allele should also be explored. |
Human | AGER | 177 | advanced glycosylation end product-specific receptor | Soluble but not sescretory protein is associated with albuminuria in type 2 diabetic paaatients, whil neither is associated with markers of glucose control or macrovascular disease Association of level in serum with albuminuria may be a marker of microvascular damage in type 2 diabetes |
Human | ADD1 | 118 | adducin 1 (alpha) | ADD1 and ACE polymorphisms in hypertension have a joint influence on albuminuria |