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Details
Link-It Detail - Disease - Acquired Immunodeficiency Syndrome
Debug Stats
  • ### Total Build Time: 79 ms 63.408 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 366 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 917 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 987 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 9.165 KB
  • CONCEPT_RELATIONSHIPS gt=3 ms Completed: 3 ms rowSize= 14.870 KB
  • CONCEPT_GENES gt=71 ms Completed: 71 ms rowSize= 35.770 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Acquired Immunodeficiency Syndrome C0001175
Definition (1)
A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin's lymphoma and Kaposi's sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Slow Virus Diseases C0037341
img HIV Infections C0019693
Ancestral Roots
RootRoot Plus OneDepthParent
img Virus Diseases C0042769img Slow Virus Diseases C00373413img Slow Virus Diseases C0037341
img Bacterial Infections and Mycoses C0004615img Infection C00213116img HIV Infections C0019693
img Virus Diseases C0042769img Sexually Transmitted Diseases C00369165img HIV Infections C0019693
img Male Urogenital Diseases C1720894img Genital Diseases, Male C00174126img HIV Infections C0019693
img Female Urogenital Diseases and Pregnancy Complications C1720765img Female Urogenital Diseases C17208877img HIV Infections C0019693
img Immune System Diseases C0021053img Immunologic Deficiency Syndromes C00210514img HIV Infections C0019693
img Virus Diseases C0042769img RNA Virus Infections C00356906img HIV Infections C0019693
Relationships (363)

Relation Types:
diso_​to_​anat : 12
diso_​to_​chem : 132
diso_​to_​diso : 187
diso_​to_​gene : 11
diso_​to_​phen : 7
diso_​to_​phys : 14


Relationships:
none : 154
associated_​with : 100
clinically_​similar : 3
disease_​has_​associated_​disease : 2
gene_​associated_​with_​disease : 10
isa : 2
may_​treat : 90
parent_​is_​cdrh : 1
use : 1
Page Size
Current 25
  Page 1 of 15
Prior Page
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Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_DISO875img Complication Aspects C1171258
DISO_to_DISO755img Complication Aspects C1171258
DISO_to_DISO708img HIV Infections C0019693
DISO_to_DISO671img HIV Infections C0019693
DISO_to_CHEM373img AIDS Drugs C0376565
DISO_to_CHEM297img AIDS Drugs C0376565
DISO_to_DISO184img AIDS Associated Opportunistic Infection C0162526
DISO_to_DISO145img AIDS Associated Opportunistic Infection C0162526
DISO_to_CHEM133img AIDS Vaccines C0085432
DISO_to_ANAT128img In Blood C0005768
DISO_to_PHEN128img Disease Outbreaks C0012652
DISO_to_DISO121img Kaposi Sarcoma C0036220
DISO_to_CHEM116img ANTIRETROVIRAL AGENTS C0599685
DISO_to_PHEN108img genetic aspects C0017399
DISO_to_PHEN106img genetic aspects C0017399
DISO_to_DISO102img AIDS SEROPOS C0019699
DISO_to_CHEM98img Anti-Retroviral Agents C0599685
DISO_to_ANAT91img In Blood C0005768
DISO_to_DISO85img Tuberculosis C0041296
DISO_to_DISO83img Neoplasms C0027651
DISO_to_CHEM76img AIDS Vaccines C0085432
DISO_to_DISO75img Sarcoma, Kaposi C0036220
DISO_to_DISO67img AIDS SEROPOS C0019699
DISO_to_DISO66img Neoplasms C0027651
DISO_to_DISO66img Tuberculosis C0041296
Genes (156)

Species:
human : 156
Page Size
Current 25
  Page 1 of 7
Prior Page
Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 25 evidence detail records.
HumanAPOBEC3H164668apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
img GENERIF, Score=827, Pubmed Id: 18945781, UMLKSK CUI: C0001175
HumanAPOBEC3G60489apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
img GAD, Score=1000, Pubmed Id: 15452227, UMLKSK CUI: C0001175
img GENERIF, Score=812, Pubmed Id: 17374143, UMLKSK CUI: C0001175
img GENERIF, Score=1000, Pubmed Id: 18362149, UMLKSK CUI: C0001175
HumanWFDC158189WAP four-disulfide core domain 1
img GENERIF, Score=694, Pubmed Id: 17942534, UMLKSK CUI: C0001175
HumanRETN56729resistin
img GENERIF, Score=660, Pubmed Id: 15741250, UMLKSK CUI: C0001175
HumanTLR954106toll-like receptor 9
img GENERIF, Score=660, Pubmed Id: 18524824, UMLKSK CUI: C0001175
img GENERIF, Score=694, Pubmed Id: 12734363, UMLKSK CUI: C0001175
HumanCPSF351692cleavage and polyadenylation specific factor 3, 73kDa
img GENERIF, Score=1000, Pubmed Id: 15194760, UMLKSK CUI: C0001175
HumanCD20930835CD209 molecule
Click here to display 8 evidence detail records.
HumanCD27429126CD274 molecule
img GENERIF, Score=694, Pubmed Id: 12468426, UMLKSK CUI: C0001175
img GENERIF, Score=1000, Pubmed Id: 18650129, UMLKSK CUI: C0001175
HumanAPOBEC3C27350apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
img GENERIF, Score=660, Pubmed Id: 17078485, UMLKSK CUI: C0001175
img GENERIF, Score=1000, Pubmed Id: 18032489, UMLKSK CUI: C0001175
HumanBBC327113BCL2 binding component 3
img GENERIF, Score=694, Pubmed Id: 15143349, UMLKSK CUI: C0001175
HumanPABPC126986poly(A) binding protein, cytoplasmic 1
img GENERIF, Score=694, Pubmed Id: 18957126, UMLKSK CUI: C0001175
HumanAIPL123746aryl hydrocarbon receptor interacting protein-like 1
img GENERIF, Score=1000, Pubmed Id: 14555765, UMLKSK CUI: C0001175
HumanBRD423476bromodomain containing 4
img GENERIF, Score=694, Pubmed Id: 17690245, UMLKSK CUI: C0001175
HumanSIRT123411sirtuin 1
img GENERIF, Score=694, Pubmed Id: 15719057, UMLKSK CUI: C0001175
HumanDICER123405dicer 1, ribonuclease type III
img GENERIF, Score=694, Pubmed Id: 17360756, UMLKSK CUI: C0001175
HumanPSIP111168PC4 and SFRS1 interacting protein 1
img GENERIF, Score=861, Pubmed Id: 17397262, UMLKSK CUI: C0001175
img GENERIF, Score=694, Pubmed Id: 16311605, UMLKSK CUI: C0001175
img GENERIF, Score=694, Pubmed Id: 16439544, UMLKSK CUI: C0001175
HumanCXCR610663chemokine (C-X-C motif) receptor 6
img GENERIF, Score=1000, Pubmed Id: 12761559, UMLKSK CUI: C0001175
HumanKHDRBS110657KH domain containing, RNA binding, signal transduction associated 1
img GENERIF, Score=694, Pubmed Id: 15701759, UMLKSK CUI: C0001175
HumanHEXIM110614hexamethylene bis-acetamide inducible 1
img GENERIF, Score=694, Pubmed Id: 16382153, UMLKSK CUI: C0001175
HumanCLEC4M10332C-type lectin domain family 4, member M
img GAD, Score=1000, Pubmed Id: 12403912, UMLKSK CUI: C0001175
img GAD, Score=1000, Pubmed Id: 12403912, UMLKSK CUI: C0001175
HumanKLRG110219killer cell lectin-like receptor subfamily G, member 1
img GENERIF, Score=1000, Pubmed Id: 16140789, UMLKSK CUI: C0001175
HumanFGFBP19982fibroblast growth factor binding protein 1
img GENERIF, Score=694, Pubmed Id: 16352855, UMLKSK CUI: C0001175
HumanMRC29902mannose receptor, C type 2
img GENERIF, Score=1000, Pubmed Id: 12645947, UMLKSK CUI: C0001175
HumanNMT29397N-myristoyltransferase 2
img GENERIF, Score=660, Pubmed Id: 18089753, UMLKSK CUI: C0001175
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0001175Acquired Immunodeficiency Syndrome0self