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Details
Link-It Detail - Disease - Acne Vulgaris
Debug Stats
  • ### Total Build Time: 112 ms 31.510 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 324 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 425 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 188 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 997 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=9 ms Completed: 9 ms rowSize= 4.081 KB
  • CONCEPT_RELATIONSHIPS gt=90 ms Completed: 90 ms rowSize= 13.680 KB
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 10.678 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.147 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Disease (1)
Acne Vulgaris C0001144
Definition (1)
A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
Semantic Types (1)
Disease or Syndrome (T047)
Parents (2)
img Sebaceous Gland Diseases C0036502
img Acneiform Eruptions C0175167
Ancestral Roots
RootRoot Plus OneDepthParent
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Sebaceous Gland Diseases C0036502
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372744img Acneiform Eruptions C0175167
img Skin and Connective Tissue Diseases C0175166img Skin Diseases C00372745img Acneiform Eruptions C0175167
Relationships (303)

Relation Types:
diso_​to_​anat : 7
diso_​to_​chem : 269
diso_​to_​diso : 25
diso_​to_​phen : 2


Relationships:
none : 51
isa : 9
location_​of : 1
mapped_​to : 3
may_​treat : 239
Page Size
Current 25
  Page 1 of 13
Prior Page
Current 1
Relation TypeCo-Occuring
Concept Count
RelationshipConcept
DISO_to_CHEM258img AGENT DERMATOL C0011625
DISO_to_CHEM144img Anti-Bacterial Agents C0279516
DISO_to_CHEM129img Anti-Bacterial Agents C0279516
DISO_to_DISO129img Complication Aspects C1171258
DISO_to_CHEM119img 13 cis Retinoic Acid C0022265
DISO_to_CHEM118img AGENT DERMATOL C0011625
DISO_to_CHEM109img 13 cis Retinoic Acid C0022265
DISO_to_CHEM90img BENZOYL PEROXIDE C0005088
DISO_to_DISO84img Cicatrix C2004491
DISO_to_DISO79img Complication Aspects C1171258
DISO_to_CHEM59img 7 Chloro 7 deoxylincomycin C0008947
DISO_to_CHEM52img Naphthalenes C0027378
DISO_to_CHEM46img Tretinoin C0040845
DISO_to_CHEM45img BENZOYL PEROXIDE C0005088
DISO_to_CHEM45img Retinoids C0035339
DISO_to_ANAT42img Skin C1123023
DISO_to_DISO40img Cicatrix C2004491
DISO_to_PHEN40img genetic aspects C0017399
DISO_to_CHEM38img 922 KERATOLYTIC AGENTS C0022585
DISO_to_CHEM37img Aminolevulinic Acid C0002563
DISO_to_CHEM35img Agents, Photosensitizing C0162713
DISO_to_CHEM32img 922 KERATOLYTIC AGENTS C0022585
DISO_to_CHEM31img 7 Chloro 7 deoxylincomycin C0008947
DISO_to_ANAT29img In Blood C0005768
DISO_to_CHEM28img Naphthalenes C0027378
Genes (10)

Species:
human : 10
SpeciesGeneGeneIdGene NameEvidence
HumanNOD264127nucleotide-binding oligomerization domain containing 2
img GENERIF, Score=861, Pubmed Id: 18640012, UMLKSK CUI: C0001144
HumanWNT454361wingless-type MMTV integration site family, member 4
img OMIM, Score=1000, UMLKSK CUI: C0001144
HumanPSTPIP19051proline-serine-threonine phosphatase interacting protein 1
img OMIM, Score=1000, UMLKSK CUI: C0001144
img OMIM, Score=1000, UMLKSK CUI: C0001144
HumanTNF7124tumor necrosis factor
img GENERIF, Score=1000, Pubmed Id: 18615253, UMLKSK CUI: C0001144
HumanTBX16899T-box 1
img OMIM, Score=833, UMLKSK CUI: C0001144
HumanS100A76278S100 calcium binding protein A7
img GENERIF, Score=694, Pubmed Id: 17033192, UMLKSK CUI: C0001144
HumanMME4311membrane metallo-endopeptidase
img GENERIF, Score=694, Pubmed Id: 12102663, UMLKSK CUI: C0001144
HumanLCN23934lipocalin 2
img GENERIF, Score=1000, Pubmed Id: 18317594, UMLKSK CUI: C0001144
HumanFGFR22263fibroblast growth factor receptor 2
img OMIM, Score=833, UMLKSK CUI: C0001144
HumanDPP41803dipeptidyl-peptidase 4
img GENERIF, Score=694, Pubmed Id: 16778789, UMLKSK CUI: C0001144
XRefs (1)

XRef Types:
cui : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
CUIimg C0001144Acne Vulgaris0self