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Details
Link-It Detail - Jax Mouse Phenotype - abnormal glomerular filtration barrier morphology
Debug Stats
  • ### Total Build Time: 11 ms 7.076 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 426 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 181 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
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  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.588 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=1 ms Completed: 1 ms rowSize= 2.367 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.187 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal glomerular filtration barrier morphology MP:0011855
Definition (1)
any structural anomaly of the highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules; its integrity is maintained by physicochemical and signalling interplay among its three core constituents -- the fenestrated endothelium of the glomerular capillaries, the glomerular basement membrane, and the filtration slits of the visceral epithelial cell (podocyte)
Synonyms (1)
"abnormal GFB morphology" EXACT
Parents (1)
img abnormal renal glomerulus morphology MP:0005325
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053678img abnormal renal glomerulus morphology MP:0005325
Genes (1)

Species:
human : 1
SpeciesGeneGeneIdGene NameEvidence
HumanVEGFA7422vascular endothelial growth factor A
img Jax MP, Pubmed Id: 12618525, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 22808199, MOUSE PHENOTYPE ID: MGI:3629960
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011855abnormal glomerular filtration barrier morphology0self