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Details
Link-It Detail - Jax Mouse Phenotype - abnormal natural killer cell mediated cytotoxicity
Debug Stats
  • ### Total Build Time: 42 ms 21.456 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 428 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 194 bytes
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  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.526 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 2.910 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=30 ms Completed: 30 ms rowSize= 14.170 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.188 KB
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Jax Mouse Phenotype (1)
abnormal natural killer cell mediated cytotoxicity MP:0011719
Definition (1)
any anomaly in the process of directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors
Synonyms (1)
"abnormal NK cell mediated cell death" EXACT
Parents (1)
img abnormal NK cell physiology MP:0010766
Children (3)
img abnormal NK cell degranulation MP:0008790
img impaired natural killer cell mediated cytotoxicity MP:0005070
img increased natural killer cell mediated cytotoxicity MP:0003080
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal NK cell physiology MP:0010766
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal NK cell physiology MP:0010766
Genes (55)

Species:
human : 55
Page Size
Current 25
  Page 1 of 3
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanKLRC4-KLRK1100528032
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanRNF19B127544ring finger protein 19B
INFERRED
HumanSH2D1B117157SH2 domain containing 1B
INFERRED
HumanCLNK116449cytokine-dependent hematopoietic cell linker
INFERRED
HumanFOXQ194234forkhead box Q1
INFERRED
HumanSLAMF757823SLAM family member 7
INFERRED
HumanTLR954106toll-like receptor 9
INFERRED
HumanCD24451744CD244 molecule, natural killer cell receptor 2B4
INFERRED
HumanIL21R50615interleukin 21 receptor
INFERRED
HumanTBX2130009T-box 21
INFERRED
HumanKLRK122914killer cell lectin-like receptor subfamily K, member 1
INFERRED
HumanHCST10870hematopoietic cell signal transducer
INFERRED
HumanCD22610666CD226 molecule
INFERRED
HumanNCR19437natural cytotoxicity triggering receptor 1
INFERRED
HumanIL18R18809interleukin 18 receptor 1
INFERRED
HumanTNFSF108743tumor necrosis factor (ligand) superfamily, member 10
INFERRED
HumanSTX118676syntaxin 11
INFERRED
HumanVAV17409vav 1 guanine nucleotide exchange factor
INFERRED
HumanTYROBP7305TYRO protein tyrosine kinase binding protein
INFERRED
HumanSTAT5B6777signal transducer and activator of transcription 5B
INFERRED
HumanSTAT5A6776signal transducer and activator of transcription 5A
INFERRED
HumanSTAT16772signal transducer and activator of transcription 1, 91kDa
INFERRED
HumanRAG25897recombination activating gene 2
INFERRED
HumanRAG15896recombination activating gene 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011719abnormal natural killer cell mediated cytotoxicity0self