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Details
Link-It Detail - Jax Mouse Phenotype - abnormal glomerular endothelium fenestra morphology
Debug Stats
  • ### Total Build Time: 49 ms 20.804 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 430 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 519 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 199 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=6 ms Completed: 6 ms rowSize= 607 bytes
  • CONCEPT_CHILDREN gt=5 ms Completed: 5 ms rowSize= 595 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=17 ms Completed: 17 ms rowSize= 4.345 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 12.831 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.188 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal glomerular endothelium fenestra morphology MP:0011454
Definition (1)
any structural anomaly of the large plasma membrane-lined circular pores that perforate the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, are not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes
Synonyms (1)
"abnormal glomerular endothelial fenestrae" EXACT
Parents (1)
img abnormal glomerular capillary endothelium morphology MP:0011453
Children (1)
img absent glomerular endothelium fenestra MP:0011455
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:000536710img abnormal glomerular capillary endothelium morphology MP:0011453
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053679img abnormal glomerular capillary endothelium morphology MP:0011453
img mammalian phenotype MP:0000001img cardiovascular system phenotype MP:00053859img abnormal glomerular capillary endothelium morphology MP:0011453
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
INFERRED
HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
img Jax MP, Pubmed Id: 17015618, MOUSE PHENOTYPE ID: MGI:1096360
img Jax MP, Pubmed Id: 15723268, MOUSE PHENOTYPE ID: MGI:2155865
img Jax MP, Pubmed Id: 18288100, MOUSE PHENOTYPE ID: MGI:2157018
img Jax MP, Pubmed Id: 11733384, MOUSE PHENOTYPE ID: MGI:3850494
HumanEHD430844EH-domain containing 4
INFERRED
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
img Jax MP, Pubmed Id: 15723268, MOUSE PHENOTYPE ID: MGI:2155865
img Jax MP, Pubmed Id: 17015618, MOUSE PHENOTYPE ID: MGI:1096360
img Jax MP, Pubmed Id: 18288100, MOUSE PHENOTYPE ID: MGI:2157018
img Jax MP, Pubmed Id: 11733384, MOUSE PHENOTYPE ID: MGI:3850494
HumanVEGFA7422vascular endothelial growth factor A
INFERRED
HumanLMX1B4010LIM homeobox transcription factor 1, beta
INFERRED
HumanFOXC22303forkhead box C2 (MFH-1, mesenchyme forkhead 1)
INFERRED
HumanCD151977CD151 molecule (Raph blood group)
img Jax MP, Pubmed Id: 18288100, MOUSE PHENOTYPE ID: MGI:2157018
img Jax MP, Pubmed Id: 17015618, MOUSE PHENOTYPE ID: MGI:1096360
img Jax MP, Pubmed Id: 11733384, MOUSE PHENOTYPE ID: MGI:3850494
img Jax MP, Pubmed Id: 15723268, MOUSE PHENOTYPE ID: MGI:2155865
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011454abnormal glomerular endothelium fenestra morphology0self