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Details
Link-It Detail - Jax Mouse Phenotype - abnormal proximal convoluted tubule brush border morphology
Debug Stats
  • ### Total Build Time: 11 ms 11.786 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 446 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 464 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 216 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 601 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.059 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.598 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=5 ms Completed: 5 ms rowSize= 6.103 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.196 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal proximal convoluted tubule brush border morphology MP:0011350
Definition (1)
any structural anomaly of the densely packed microvilli that cover the luminal surface of epithelial cells of the proximal convoluted tubule; microvilli increase the luminal surface area of cells, sense the fluid flow in the tubule lumen and convert this information via biochemical responses into reabsorption
Synonyms (1)
"abnormal renal proximal tubular striated border morphology" EXACT
Parents (1)
img abnormal proximal convoluted tubule morphology MP:0004756
Children (2)
img absent proximal convoluted tubule brush border MP:0011351
img proximal convoluted tubule brush border loss MP:0011352
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053678img abnormal proximal convoluted tubule morphology MP:0004756
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanAQP11282679aquaporin 11
INFERRED
HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
INFERRED
HumanINVS27130inversin
INFERRED
HumanTLR47099toll-like receptor 4
img Jax MP, Pubmed Id: 18974879, MOUSE PHENOTYPE ID: MGI:96824
HumanTCF216943transcription factor 21
INFERRED
HumanREN5972renin
INFERRED
HumanPTGS25743prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
INFERRED
HumanMYO1E4643myosin IE
INFERRED
HumanMEP1B4225meprin A, beta
INFERRED
HumanMEP1A4224meprin A, alpha (PABA peptide hydrolase)
INFERRED
HumanHMOX13162heme oxygenase (decycling) 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011350abnormal proximal convoluted tubule brush border morphology0self