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Details
Link-It Detail - Jax Mouse Phenotype - abnormal renal glomerulus basement membrane thickness
Debug Stats
  • ### Total Build Time: 20 ms 30.271 KB
  • CONCEPT_NAME gt=1 ms Completed: 1 ms rowSize= 434 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 354 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 180 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 609 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 1.076 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 1.605 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 24.714 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.190 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal renal glomerulus basement membrane thickness MP:0011349
Definition (1)
increased or decreased width of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule
Synonyms (1)
"abnormal GBM thickness" EXACT
Parents (1)
img abnormal renal glomerulus basement membrane morphology MP:0011348
Children (2)
img increased renal glomerulus basement membrane thickness MP:0011409
img decreased renal glomerulus basement membrane thickness MP:0011859
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053678img abnormal renal glomerulus basement membrane morphology MP:0011348
Genes (26)

Species:
human : 26
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
INFERRED
HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
INFERRED
HumanEHD430844EH-domain containing 4
INFERRED
HumanBCL2L1110018BCL2-like 11 (apoptosis facilitator)
INFERRED
HumanMTSS19788metastasis suppressor 1
INFERRED
HumanWT17490Wilms tumor 1
INFERRED
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
INFERRED
HumanVEGFA7422vascular endothelial growth factor A
img Jax MP, Pubmed Id: 20847057, MOUSE PHENOTYPE ID: MGI:104688
img Jax MP, Pubmed Id: 17804483, MOUSE PHENOTYPE ID: MGI:1201674
img Jax MP, Pubmed Id: 8956999, MOUSE PHENOTYPE ID: MGI:104688
img Jax MP, Pubmed Id: 12651605, MOUSE PHENOTYPE ID: MGI:893592
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
HumanPKN15585protein kinase N1
INFERRED
HumanMYO1E4643myosin IE
INFERRED
HumanMYH94627myosin, heavy chain 9, non-muscle
INFERRED
HumanSMAD34088SMAD family member 3
img Jax MP, Pubmed Id: 12651605, MOUSE PHENOTYPE ID: MGI:893592
img Jax MP, Pubmed Id: 17804483, MOUSE PHENOTYPE ID: MGI:1201674
img Jax MP, Pubmed Id: 20847057, MOUSE PHENOTYPE ID: MGI:104688
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 8956999, MOUSE PHENOTYPE ID: MGI:104688
HumanLMX1B4010LIM homeobox transcription factor 1, beta
INFERRED
HumanLEPR3953leptin receptor
INFERRED
HumanLEP3952leptin
INFERRED
HumanLAMB23913laminin, beta 2 (laminin S)
INFERRED
HumanLAMA53911laminin, alpha 5
INFERRED
HumanITGA33675integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
INFERRED
HumanGRM12911glutamate receptor, metabotropic 1
INFERRED
HumanGDNF2668glial cell derived neurotrophic factor
INFERRED
HumanE2F21870E2F transcription factor 2
INFERRED
HumanCOL4A31285collagen, type IV, alpha 3 (Goodpasture antigen)
img Jax MP, Pubmed Id: 8956999, MOUSE PHENOTYPE ID: MGI:104688
img Jax MP, Pubmed Id: 12651605, MOUSE PHENOTYPE ID: MGI:893592
img Jax MP, Pubmed Id: 20847057, MOUSE PHENOTYPE ID: MGI:104688
img Jax MP, Pubmed Id: 12039984, MOUSE PHENOTYPE ID: MGI:103178
img Jax MP, Pubmed Id: 17804483, MOUSE PHENOTYPE ID: MGI:1201674
HumanCD151977CD151 molecule (Raph blood group)
INFERRED
HumanDDR1780discoidin domain receptor tyrosine kinase 1
INFERRED
HumanASIP434agouti signaling protein
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011349abnormal renal glomerulus basement membrane thickness0self