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Details
Link-It Detail - Jax Mouse Phenotype - abnormal renal glomerulus basement membrane morphology
Debug Stats
  • ### Total Build Time: 50 ms 21.359 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 436 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 474 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 181 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 590 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 610 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.587 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=35 ms Completed: 35 ms rowSize= 16.199 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.191 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal renal glomerulus basement membrane morphology MP:0011348
Definition (1)
any structural anomaly of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter
Synonyms (1)
"abnormal GBM morphology" EXACT
Parents (1)
img abnormal renal corpuscle morphology MP:0002827
Children (1)
img abnormal renal glomerulus basement membrane thickness MP:0011349
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053677img abnormal renal corpuscle morphology MP:0002827
Genes (36)

Species:
human : 36
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Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGSTK1373156glutathione S-transferase kappa 1
Click here to display 40 evidence detail records.
HumanPDSS257107prenyl (decaprenyl) diphosphate synthase, subunit 2
Click here to display 40 evidence detail records.
HumanCRIM151232cysteine rich transmembrane BMP regulator 1 (chordin-like)
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HumanRRM2B50484ribonucleotide reductase M2 B (TP53 inducible)
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HumanEHD430844EH-domain containing 4
Click here to display 40 evidence detail records.
HumanGNE10020glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
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HumanBCL2L1110018BCL2-like 11 (apoptosis facilitator)
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HumanMTSS19788metastasis suppressor 1
INFERRED
HumanNPHS27827nephrosis 2, idiopathic, steroid-resistant (podocin)
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HumanWT17490Wilms tumor 1
INFERRED
HumanVHL7428von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
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HumanVEGFA7422vascular endothelial growth factor A
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HumanSYK6850spleen tyrosine kinase
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HumanPKN15585protein kinase N1
INFERRED
HumanMYO1E4643myosin IE
Click here to display 40 evidence detail records.
HumanMYH94627myosin, heavy chain 9, non-muscle
INFERRED
HumanSMAD34088SMAD family member 3
INFERRED
HumanLMX1B4010LIM homeobox transcription factor 1, beta
Click here to display 40 evidence detail records.
HumanLEPR3953leptin receptor
INFERRED
HumanLEP3952leptin
INFERRED
HumanLAMB23913laminin, beta 2 (laminin S)
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HumanLAMA53911laminin, alpha 5
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HumanITGA33675integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
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HumanCFH3075complement factor H
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HumanGRM12911glutamate receptor, metabotropic 1
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XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011348abnormal renal glomerulus basement membrane morphology0self