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Details
Link-It Detail - Jax Mouse Phenotype - abnormal tubuloglomerular feedback response
Debug Stats
  • ### Total Build Time: 52 ms 8.898 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 464 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 179 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 581 bytes
  • CONCEPT_CHILDREN gt=9 ms Completed: 9 ms rowSize= 1.054 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=8 ms Completed: 8 ms rowSize= 1.578 KB
  • CONCEPT_RELATIONSHIPS gt=2 ms Completed: 2 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 3.342 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal tubuloglomerular feedback response MP:0011295
Definition (1)
any anomaly in the blood flow control mechanism that is operated in the juxtaglomerular apparatus of the kidney and involved in renal autoregulation by limiting changes in the glomerular filtration rate. TGF responds to changes in the concentration of NaCl in the tubular fluid at the level of the macula densa
Synonyms (1)
"abnormal TGF response" EXACT
Parents (1)
img abnormal kidney physiology MP:0002136
Children (2)
img decreased tubuloglomerular feedback response MP:0011296
img absent tubuloglomerular feedback response MP:0011297
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img renal/urinary system phenotype MP:00053675img abnormal kidney physiology MP:0002136
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanSLC12A16557solute carrier family 12 (sodium/potassium/chloride transporter), member 1
img Jax MP, Pubmed Id: 17215439, MOUSE PHENOTYPE ID: MGI:103150
img Jax MP, Pubmed Id: 16807402, MOUSE PHENOTYPE ID: MGI:103150
HumanKCNJ13758potassium inwardly-rectifying channel, subfamily J, member 1
INFERRED
HumanADORA1134adenosine A1 receptor
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011295abnormal tubuloglomerular feedback response0self