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Details
Link-It Detail - Jax Mouse Phenotype - abnormal lung-associated mesenchyme development
Debug Stats
  • ### Total Build Time: 21 ms 13.442 KB
  • CONCEPT_NAME gt=15 ms Completed: 15 ms rowSize= 422 bytes
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  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 8.536 KB
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Jax Mouse Phenotype (1)
abnormal lung-associated mesenchyme development MP:0011142
Definition (1)
abnormality in the formation of the lung tissue comprised of multiple cell types (including connective tissue, endothelial cells, lymphatics, smooth muscle cells surrounding airways and blood vessels, myofibroblasts involved in septum formation, and cartilage-forming cells in the trachea), with most cells thought to be derived from the splanchnic mesenchyme, and other cells (endothelial, smooth muscle) believed to invade the lung as it expands; lung mesenchyme is a critical determinant of the shape and size of the developing lung, the extent and patterning of epithelial branching, and the formation of the pulmonary vasculature and interstitial mesenchymal components of the adult lung
Synonyms (1)
"abnormal lung mesenchyme development" EXACT
Parents (1)
img abnormal lung development MP:0001176
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img respiratory system phenotype MP:00053886img abnormal lung development MP:0001176
Genes (3)

Species:
human : 3
SpeciesGeneGeneIdGene NameEvidence
HumanTWIST2117581twist basic helix-loop-helix transcription factor 2
img Jax MP, Pubmed Id: 16510470, MOUSE PHENOTYPE ID: MGI:1916782
img Jax MP, Pubmed Id: 19686689, MOUSE PHENOTYPE ID: MGI:98954
img Jax MP, Pubmed Id: 23023706, MOUSE PHENOTYPE ID: MGI:104685
HumanHOPX84525HOP homeobox
img Jax MP, Pubmed Id: 16510470, MOUSE PHENOTYPE ID: MGI:1916782
img Jax MP, Pubmed Id: 23023706, MOUSE PHENOTYPE ID: MGI:104685
img Jax MP, Pubmed Id: 19686689, MOUSE PHENOTYPE ID: MGI:98954
HumanWNT27472wingless-type MMTV integration site family member 2
img Jax MP, Pubmed Id: 23023706, MOUSE PHENOTYPE ID: MGI:104685
img Jax MP, Pubmed Id: 19686689, MOUSE PHENOTYPE ID: MGI:98954
img Jax MP, Pubmed Id: 16510470, MOUSE PHENOTYPE ID: MGI:1916782
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0011142abnormal lung-associated mesenchyme development0self