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Details
Link-It Detail - Jax Mouse Phenotype - abnormal pulmonary neuroendocrine body morphology
Debug Stats
  • ### Total Build Time: 7 ms 18.810 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 426 bytes
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Jax Mouse Phenotype (1)
abnormal pulmonary neuroendocrine body morphology MP:0010918
Definition (1)
any structural anomaly of the corpuscular, organoid structures composed of PNECs, found as distinctive innervated clusters only within intrapulmonary airways, where they appear concentrated at airway branch points; NEBs reach from the basement membrane to the airway lumen and are thought to function as oxygen sensors
Synonyms (1)
"abnormal pulmonary neuroendocrine bodies" BROAD
Parents (1)
img abnormal lung epithelium morphology MP:0006382
Children (3)
img increased number of pulmonary neuroendocrine bodies MP:0010919
img absent pulmonary neuroendocrine bodies MP:0010921
img decreased number of pulmonary neuroendocrine bodies MP:0010920
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img respiratory system phenotype MP:00053886img abnormal lung epithelium morphology MP:0006382
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanPTEN5728phosphatase and tensin homolog
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:2151253
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:109583
HumanNEUROD14760neuronal differentiation 1
INFERRED
HumanHES13280hairy and enhancer of split 1, (Drosophila)
INFERRED
HumanFBN12200fibrillin 1
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:2151253
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:104735
HumanCALCA796calcitonin-related polypeptide alpha
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:2151253
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 23047698, MOUSE PHENOTYPE ID: MGI:104735
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
HumanASCL1429achaete-scute complex homolog 1 (Drosophila)
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010918abnormal pulmonary neuroendocrine body morphology0self