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Details
Link-It Detail - Jax Mouse Phenotype - increased solitary pulmonary neuroendocrine cell number
Debug Stats
  • ### Total Build Time: 18 ms 23.404 KB
  • CONCEPT_NAME gt=2 ms Completed: 2 ms rowSize= 438 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 716 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 208 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 613 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 2.982 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=10 ms Completed: 10 ms rowSize= 17.148 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.192 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased solitary pulmonary neuroendocrine cell number MP:0010915
Definition (1)
increased number of the specialized non-ciliated, round- to oval-shaped epithelial cells found as solitary cells in the nasal respiratory epithelium and the mucosa of the larynx, trachea and bronchi up to the terminal bronchioles; PNECs are the first cell type to differentiate during early fetal lung development, produce amine (e.g. serotonin, 5-HT) and peptides (e.g. bombesin, calcitonin) with growth factor-like properties, and appear to be involved in processes ranging from lung development and respiratory physiology to repair, disease and carcinogenesis
Synonyms (1)
"increased respiratory enterochromaffin cell number" EXACT
Parents (1)
img abnormal solitary pulmonary neuroendocrine cell morphology MP:0010914
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img endocrine/exocrine gland phenotype MP:00053797img abnormal solitary pulmonary neuroendocrine cell morphology MP:0010914
img mammalian phenotype MP:0000001img nervous system phenotype MP:00036317img abnormal solitary pulmonary neuroendocrine cell morphology MP:0010914
Genes (4)

Species:
human : 4
SpeciesGeneGeneIdGene NameEvidence
HumanPOFUT123509protein O-fucosyltransferase 1
img Jax MP, Pubmed Id: 19502490, MOUSE PHENOTYPE ID: MGI:2153207
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
img Jax MP, Pubmed Id: 17921358, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
HumanPTEN5728phosphatase and tensin homolog
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
img Jax MP, Pubmed Id: 17921358, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
img Jax MP, Pubmed Id: 19502490, MOUSE PHENOTYPE ID: MGI:2153207
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
HumanHES13280hairy and enhancer of split 1, (Drosophila)
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
img Jax MP, Pubmed Id: 19502490, MOUSE PHENOTYPE ID: MGI:2153207
img Jax MP, Pubmed Id: 17921358, MOUSE PHENOTYPE ID: MGI:109583
HumanFBN12200fibrillin 1
img Jax MP, Pubmed Id: 19502490, MOUSE PHENOTYPE ID: MGI:2153207
img Jax MP, Pubmed Id: 18339630, MOUSE PHENOTYPE ID: MGI:95489
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
img Jax MP, Pubmed Id: 17921358, MOUSE PHENOTYPE ID: MGI:109583
img Jax MP, Pubmed Id: 10952889, MOUSE PHENOTYPE ID: MGI:104853
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010915increased solitary pulmonary neuroendocrine cell number0self