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Details
Link-It Detail - Jax Mouse Phenotype - abnormal activation-induced cell death of T cells
Debug Stats
  • ### Total Build Time: 6 ms 10.156 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 426 bytes
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Jax Mouse Phenotype (1)
abnormal activation-induced cell death of T cells MP:0010670
Definition (1)
any anomaly in the process of the type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors
Synonyms (1)
"abnormal AICD" BROAD
Parents (2)
img abnormal apoptosis MP:0001648
img abnormal T cell apoptosis MP:0006412
Children (2)
img decreased activation-induced cell death of T cells MP:0010677
img increased activation-induced cell death of T cells MP:0010676
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal apoptosis MP:0001648
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal T cell apoptosis MP:0006412
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal T cell apoptosis MP:0006412
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanHAVCR284868hepatitis A virus cellular receptor 2
INFERRED
HumanCD44960CD44 molecule (Indian blood group)
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010670abnormal activation-induced cell death of T cells0self