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Details
Link-It Detail - Jax Mouse Phenotype - abnormal activation-induced cell death of T cells
Debug Stats
  • ### Total Build Time: 83 ms 10.197 KB
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  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 1.420 KB
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Jax Mouse Phenotype (1)
abnormal activation-induced cell death of T cells MP:0010670
Definition (1)
any anomaly in the process of the type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors
Synonyms (1)
"abnormal activation-induced cell death of T lymphocytes" EXACT
Parents (2)
img abnormal T cell apoptosis MP:0006412
img abnormal apoptosis MP:0001648
Children (2)
img decreased activation-induced cell death of T cells MP:0010677
img increased activation-induced cell death of T cells MP:0010676
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal T cell apoptosis MP:0006412
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal T cell apoptosis MP:0006412
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal apoptosis MP:0001648
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanHAVCR284868hepatitis A virus cellular receptor 2
INFERRED
HumanCD44960CD44 molecule (Indian blood group)
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010670abnormal activation-induced cell death of T cells0self