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Details
Link-It Detail - Jax Mouse Phenotype - abnormal activation-induced B cell apoptosis
Debug Stats
  • ### Total Build Time: 84 ms 12.759 KB
  • CONCEPT_NAME gt=9 ms Completed: 9 ms rowSize= 416 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 407 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 207 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=30 ms Completed: 30 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=10 ms Completed: 10 ms rowSize= 1.011 KB
  • CONCEPT_CHILDREN gt=10 ms Completed: 10 ms rowSize= 1.059 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 5.562 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=21 ms Completed: 21 ms rowSize= 2.795 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.182 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal activation-induced B cell apoptosis MP:0010669
Definition (1)
any anomaly in the process in which B cell apoptosis occurs upon engagement of either the B cell receptor or CD40, but not both; the engagement leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death
Synonyms (1)
"abnormal activation-induced cell death of B cells" EXACT
Parents (2)
img abnormal B cell apoptosis MP:0008781
img abnormal apoptosis MP:0001648
Children (2)
img increased activation-induced B cell apoptosis MP:0010674
img decreased activation-induced B cell apoptosis MP:0010675
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal B cell apoptosis MP:0008781
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal B cell apoptosis MP:0008781
img mammalian phenotype MP:0000001img cellular phenotype MP:00053847img abnormal B cell apoptosis MP:0008781
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal apoptosis MP:0001648
Genes (5)

Species:
human : 5
SpeciesGeneGeneIdGene NameEvidence
HumanSPPL2A84888signal peptide peptidase like 2A
INFERRED
HumanOTUD7B56957OTU domain containing 7B
INFERRED
HumanPKN15585protein kinase N1
INFERRED
HumanNFKBIA4792nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
INFERRED
HumanBCL6604B-cell CLL/lymphoma 6
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010669abnormal activation-induced B cell apoptosis0self