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Details
Link-It Detail - Jax Mouse Phenotype - increased pituitary gland tumor incidence
Debug Stats
  • ### Total Build Time: 46 ms 20.017 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 279 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=12 ms Completed: 12 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 1.038 KB
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.530 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.907 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=26 ms Completed: 26 ms rowSize= 12.545 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased pituitary gland tumor incidence MP:0010320
Definition (1)
greater than the expected number of neoplams in the pituitary gland occurring in a specific population in a given time period
Parents (2)
img increased gland tumor incidence MP:0010288
img increased nervous system tumor incidence MP:0010281
Children (3)
img increased pituitary adenoma incidence MP:0002041
img increased pituitary adenohypophysis tumor incidence MP:0010350
img increased pituitary melanotroph tumor incidence MP:0010351
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img tumorigenesis MP:00020068img increased gland tumor incidence MP:0010288
img mammalian phenotype MP:0000001img tumorigenesis MP:00020068img increased nervous system tumor incidence MP:0010281
Genes (24)

Species:
human : 24
SpeciesGeneGeneIdGene NameEvidence
HumanRINT160561RAD50 interactor 1
INFERRED
HumanCUL923113cullin 9
Click here to display 27 evidence detail records.
HumanAIP9049aryl hydrocarbon receptor interacting protein
INFERRED
HumanPRDM27799PR domain containing 2, with ZNF domain
INFERRED
HumanTHRB7068thyroid hormone receptor, beta
INFERRED
HumanRBL15933retinoblastoma-like 1 (p107)
Click here to display 27 evidence detail records.
HumanKDM5A5927lysine (K)-specific demethylase 5A
Click here to display 27 evidence detail records.
HumanRB15925retinoblastoma 1
Click here to display 27 evidence detail records.
HumanRAG15896recombination activating gene 1
INFERRED
HumanPRL5617prolactin
INFERRED
HumanPRKAR1A5573protein kinase, cAMP-dependent, regulatory, type I, alpha
Click here to display 27 evidence detail records.
HumanPOMC5443proopiomelanocortin
INFERRED
HumanNF24771neurofibromin 2 (merlin)
INFERRED
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
INFERRED
HumanMEN14221multiple endocrine neoplasia I
Click here to display 27 evidence detail records.
HumanIFNG3458interferon, gamma
INFERRED
HumanFOXO32309forkhead box O3
INFERRED
HumanE2F41874E2F transcription factor 4, p107/p130-binding
Click here to display 27 evidence detail records.
HumanE2F11869E2F transcription factor 1
Click here to display 27 evidence detail records.
HumanDRD21813dopamine receptor D2
INFERRED
HumanCDKN2D1032cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
INFERRED
HumanCDKN2C1031cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
INFERRED
HumanCDKN2B1030cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
INFERRED
HumanCDKN1B1027cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Click here to display 27 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010320increased pituitary gland tumor incidence0self