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Details
Link-It Detail - Jax Mouse Phenotype - increased skeletal tumor incidence
Debug Stats
  • ### Total Build Time: 20 ms 30.098 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 311 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 598 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 1.450 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.578 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 24.479 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased skeletal tumor incidence MP:0010280
Definition (1)
greater than the expected number of neoplasms in the skeletal tissue, usually in the form of a distinct mass, in a specific population in a given time period
Parents (1)
img increased organ/body region tumor incidence MP:0010274
Children (3)
img increased osteoma incidence MP:0010313
img osteochondroma MP:0010079
img osteosarcoma MP:0003789
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img tumorigenesis MP:00020067img increased organ/body region tumor incidence MP:0010274
Genes (21)

Species:
human : 21
SpeciesGeneGeneIdGene NameEvidence
HumanMOB1B92597MOB kinase activator 1B
INFERRED
HumanSAV160485salvador homolog 1 (Drosophila)
INFERRED
HumanWWOX51741WW domain containing oxidoreductase
img Jax MP, Pubmed Id: 19059914, MOUSE PHENOTYPE ID: MGI:107655
img Jax MP, Pubmed Id: 20940146
img Jax MP, Pubmed Id: 19059914, MOUSE PHENOTYPE ID: MGI:4839780
img Jax MP, Pubmed Id: 15221010, MOUSE PHENOTYPE ID: MGI:3047154
img Jax MP, Pubmed Id: 23254685, MOUSE PHENOTYPE ID: MGI:1931237
img Jax MP, Pubmed Id: 20421483
img Jax MP, Pubmed Id: 20421483, MOUSE PHENOTYPE ID: MGI:104878
HumanWIF111197WNT inhibitory factor 1
INFERRED
HumanDMTF19988cyclin D binding myb-like transcription factor 1
INFERRED
HumanTP638626tumor protein p63
INFERRED
HumanMAD1L18379MAD1 mitotic arrest deficient-like 1 (yeast)
INFERRED
HumanTP537157tumor protein p53
INFERRED
HumanTHBS17057thrombospondin 1
INFERRED
HumanSTK116794serine/threonine kinase 11
INFERRED
HumanREV3L5980REV3-like, polymerase (DNA directed), zeta, catalytic subunit
INFERRED
HumanPRKAR1A5573protein kinase, cAMP-dependent, regulatory, type I, alpha
img Jax MP, Pubmed Id: 23254685, MOUSE PHENOTYPE ID: MGI:1931237
img Jax MP, Pubmed Id: 20421483
img Jax MP, Pubmed Id: 20940146
img Jax MP, Pubmed Id: 15221010, MOUSE PHENOTYPE ID: MGI:3047154
img Jax MP, Pubmed Id: 19059914, MOUSE PHENOTYPE ID: MGI:4839780
img Jax MP, Pubmed Id: 20421483, MOUSE PHENOTYPE ID: MGI:104878
img Jax MP, Pubmed Id: 19059914, MOUSE PHENOTYPE ID: MGI:107655
HumanPRDX15052peroxiredoxin 1
INFERRED
HumanNF24771neurofibromin 2 (merlin)
INFERRED
HumanMSH24436mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
INFERRED
HumanMDM24193MDM2 oncogene, E3 ubiquitin protein ligase
INFERRED
HumanIFNGR13459interferon gamma receptor 1
img Jax MP, Pubmed Id: 19059914, MOUSE PHENOTYPE ID: MGI:4839780
img Jax MP, Pubmed Id: 23254685, MOUSE PHENOTYPE ID: MGI:1931237
img Jax MP, Pubmed Id: 20421483, MOUSE PHENOTYPE ID: MGI:104878
img Jax MP, Pubmed Id: 19059914, MOUSE PHENOTYPE ID: MGI:107655
img Jax MP, Pubmed Id: 20940146
img Jax MP, Pubmed Id: 20421483
img Jax MP, Pubmed Id: 15221010, MOUSE PHENOTYPE ID: MGI:3047154
HumanEXT12131exostosin glycosyltransferase 1
INFERRED
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
INFERRED
HumanBRCA2675breast cancer 2, early onset
INFERRED
HumanACVR190activin A receptor, type I
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0010280increased skeletal tumor incidence0self