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Details
Link-It Detail - Jax Mouse Phenotype - foam cell reticulosis
Debug Stats
  • ### Total Build Time: 69 ms 13.145 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 370 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 592 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 184 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=12 ms Completed: 12 ms rowSize= 584 bytes
  • CONCEPT_CHILDREN gt=12 ms Completed: 12 ms rowSize= 602 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=12 ms Completed: 12 ms rowSize= 1.569 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=22 ms Completed: 22 ms rowSize= 7.994 KB
  • CONCEPT_XREFS gt=4 ms Completed: 4 ms rowSize= 1.159 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
foam cell reticulosis MP:0009841
Definition (1)
an increase in cells with a vacuolated appearance due to abnormal deposition and retention of lipoproteins and derived from or related to the group of cells having the ability to take up and sequester inert particles and vital dyes, including macrophages and macrophage precursors, specialized endothelial cells lining the sinusoids of the liver, spleen, and bone marrow, and macrophages of lymphatic tissue and fibroblasts of bone marrow
Synonyms (1)
"increased foam cell number" EXACT
Parents (1)
img abnormal foam cell morphology MP:0009840
Children (1)
img increased macrophage derived foam cell number MP:0004778
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053845img abnormal foam cell morphology MP:0009840
Genes (11)

Species:
human : 11
SpeciesGeneGeneIdGene NameEvidence
HumanGPR116221395G protein-coupled receptor 116
INFERRED
HumanPLA2G1523659phospholipase A2, group XV
INFERRED
HumanNR1H310062nuclear receptor subfamily 1, group H, member 3
INFERRED
HumanABCG19619ATP-binding cassette, sub-family G (WHITE), member 1
INFERRED
HumanSMPD16609sphingomyelin phosphodiesterase 1, acid lysosomal
INFERRED
HumanCX3CL16376chemokine (C-X3-C motif) ligand 1
INFERRED
HumanMAPK95601mitogen-activated protein kinase 9
INFERRED
HumanNPC14864Niemann-Pick disease, type C1
img Jax MP, Pubmed Id: 20007718, MOUSE PHENOTYPE ID: MGI:1097712
img Jax MP, Pubmed Id: 21896731, MOUSE PHENOTYPE ID: MGI:1097712
img Jax MP, Pubmed Id: 20007718, MOUSE PHENOTYPE ID: MGI:1097712
img Jax MP
HumanAPOC3345apolipoprotein C-III
INFERRED
HumanAPOA4337apolipoprotein A-IV
INFERRED
HumanAPOA1335apolipoprotein A-I
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009841foam cell reticulosis0self