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Details
Link-It Detail - Jax Mouse Phenotype - gastrointestinal stromal tumor
Debug Stats
  • ### Total Build Time: 40 ms 14.852 KB
  • CONCEPT_NAME gt=7 ms Completed: 7 ms rowSize= 388 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 669 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 163 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=13 ms Completed: 13 ms rowSize= 597 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.577 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=14 ms Completed: 14 ms rowSize= 10.180 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.168 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
gastrointestinal stromal tumor MP:0009515
Definition (1)
non-epithelial, mesenchymal tumors of the gastrointestinal tract, thought to originate from the interstitial cells of Cajal, the pacemaker cells that regulate peristalsis in the digestive tract; approximately 70% of GISTs develop in the stomach, 20% in the small intestine, and less than 10% in the esophagus, colon, and rectum; GISTs are tumors of connective tissue, i.e. sarcomas, account for 1-3% of all gastrointestinal malignancies in human, and are typically more cellular than other gastrointestinal sarcomas
Synonyms (1)
"GISTs" EXACT
Parents (1)
img increased gastrointestinal tumor incidence MP:0010279
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img tumorigenesis MP:00020069img increased gastrointestinal tumor incidence MP:0010279
Genes (2)

Species:
human : 2
SpeciesGeneGeneIdGene NameEvidence
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
img Jax MP, Pubmed Id: 12754375, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 16061643, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 18098338, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 14665695, MOUSE PHENOTYPE ID: MGI:104738
img Jax MP, Pubmed Id: 16061643, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 18098338, MOUSE PHENOTYPE ID: MGI:96677
HumanCDKN2A1029cyclin-dependent kinase inhibitor 2A
img Jax MP, Pubmed Id: 16061643, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 18098338, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 12754375, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 18098338, MOUSE PHENOTYPE ID: MGI:96677
img Jax MP, Pubmed Id: 14665695, MOUSE PHENOTYPE ID: MGI:104738
img Jax MP, Pubmed Id: 16061643, MOUSE PHENOTYPE ID: MGI:96677
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009515gastrointestinal stromal tumor0self