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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interleukin-21 secretion
Debug Stats
  • ### Total Build Time: 24 ms 8.665 KB
  • CONCEPT_NAME gt=14 ms Completed: 14 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 379 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 182 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 585 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.037 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.575 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=4 ms Completed: 4 ms rowSize= 3.233 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal interleukin-21 secretion MP:0009056
Definition (1)
anomaly in the production or release of a pleiotropic cytokine that regulates immunoglobulin production, plasma cell and Th17 T cell differentiation, CD8+ T cell expansion, and inhibits antigen presentation by dendritic cells
Synonyms (1)
"abnormal IL-21 secretion" EXACT
Parents (1)
img abnormal interleukin secretion MP:0008568
Children (2)
img decreased interleukin-21 secretion MP:0009058
img increased interleukin-21 secretion MP:0009057
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interleukin secretion MP:0008568
Genes (6)

Species:
human : 6
SpeciesGeneGeneIdGene NameEvidence
HumanRNF12879589ring finger protein 128, E3 ubiquitin protein ligase
INFERRED
HumanIL21R50615interleukin 21 receptor
INFERRED
HumanICOS29851inducible T-cell co-stimulator
INFERRED
HumanBATF10538basic leucine zipper transcription factor, ATF-like
INFERRED
HumanCD848832CD84 molecule
INFERRED
HumanSH2D1A4068SH2 domain containing 1A
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0009056abnormal interleukin-21 secretion0self