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Details
Link-It Detail - Jax Mouse Phenotype - increased sensitivity to induced cell death
Debug Stats
  • ### Total Build Time: 270 ms 22.092 KB
  • CONCEPT_NAME gt=8 ms Completed: 8 ms rowSize= 414 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 267 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 200 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 582 bytes
  • CONCEPT_CHILDREN gt=1 ms Completed: 1 ms rowSize= 2.030 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 1.567 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=253 ms Completed: 253 ms rowSize= 15.740 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.181 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased sensitivity to induced cell death MP:0008943
Definition (1)
decrease in the exposure level to an agent that is required to induce cessation of function at the cellular level
Synonyms (1)
"decreased resistance to induced cell death" EXACT
Parents (1)
img abnormal induced cell death MP:0008942
Children (4)
img increased cellular sensitivity to ionizing radiation MP:0004227
img increased cellular sensitivity to oxidative stress MP:0008412
img increased cellular sensitivity to alkylating agents MP:0008402
img increased cellular sensitivity to ultraviolet irradiation MP:0008410
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img cellular phenotype MP:00053846img abnormal induced cell death MP:0008942
Genes (133)

Species:
human : 133
Page Size
Current 25
  Page 1 of 6
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanMCM9254394minichromosome maintenance complex component 9
INFERRED
HumanRAD9B144715RAD9 homolog B (S. pombe)
Click here to display 39 evidence detail records.
HumanE2F7144455E2F transcription factor 7
INFERRED
HumanVASN114990vasorin
Click here to display 39 evidence detail records.
HumanITPRIP85450inositol 1,4,5-trisphosphate receptor interacting protein
Click here to display 39 evidence detail records.
HumanSUV420H284787suppressor of variegation 4-20 homolog 2 (Drosophila)
INFERRED
HumanMCM884515minichromosome maintenance complex component 8
INFERRED
HumanSESN283667sestrin 2
INFERRED
HumanMXD383463MAX dimerization protein 3
INFERRED
HumanNHEJ179840nonhomologous end-joining factor 1
Click here to display 39 evidence detail records.
HumanMCPH179648microcephalin 1
INFERRED
HumanRNASEH2B79621ribonuclease H2, subunit B
INFERRED
HumanMAPKAP179109mitogen-activated protein kinase associated protein 1
INFERRED
HumanPINK165018PTEN induced putative kinase 1
Click here to display 39 evidence detail records.
HumanDCLRE1C64421DNA cross-link repair 1C
INFERRED
HumanRIF155183RAP1 interacting factor homolog (yeast)
INFERRED
HumanUSP4755031ubiquitin specific peptidase 47
INFERRED
HumanCC2D1A54862coiled-coil and C2 domain containing 1A
INFERRED
HumanUIMC151720ubiquitin interaction motif containing 1
INFERRED
HumanSIRT651548sirtuin 6
INFERRED
HumanSIRT751547sirtuin 7
Click here to display 39 evidence detail records.
HumanPOLK51426polymerase (DNA directed) kappa
INFERRED
HumanAPEX227301APEX nuclease (apurinic/apyrimidinic endonuclease) 2
INFERRED
HumanAPPL126060adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Click here to display 39 evidence detail records.
HumanRAD54B25788RAD54 homolog B (S. cerevisiae)
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008943increased sensitivity to induced cell death0self