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Details
Link-It Detail - Jax Mouse Phenotype - abnormal mast cell degranulation
Debug Stats
  • ### Total Build Time: 29 ms 22.362 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 392 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 305 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 195 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 584 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.035 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=4 ms Completed: 4 ms rowSize= 1.574 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=15 ms Completed: 15 ms rowSize= 16.997 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.170 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal mast cell degranulation MP:0008763
Definition (1)
abnormalities in the exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell
Synonyms (1)
"abnormal mast cell granule exocytosis" EXACT
Parents (1)
img abnormal mast cell physiology MP:0002423
Children (2)
img increased mast cell degranulation MP:0008764
img decreased mast cell degranulation MP:0008765
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal mast cell physiology MP:0002423
Genes (22)

Species:
human : 22
SpeciesGeneGeneIdGene NameEvidence
HumanSPRED1161742sprouty-related, EVH1 domain containing 1
INFERRED
HumanESPN83715espin
img Jax MP, Pubmed Id: 8962054, MOUSE PHENOTYPE ID: MGI:1861630
img Jax MP, Pubmed Id: 12817015, MOUSE PHENOTYPE ID: MGI:104847
img Jax MP, Pubmed Id: 19805319, MOUSE PHENOTYPE ID: MGI:1341867
HumanTRIB357761tribbles homolog 3 (Drosophila)
INFERRED
HumanCORO1A11151coronin, actin binding protein, 1A
INFERRED
HumanMMP2410893matrix metallopeptidase 24 (membrane-inserted)
img Jax MP, Pubmed Id: 12817015, MOUSE PHENOTYPE ID: MGI:104847
img Jax MP, Pubmed Id: 8962054, MOUSE PHENOTYPE ID: MGI:1861630
img Jax MP, Pubmed Id: 19805319, MOUSE PHENOTYPE ID: MGI:1341867
HumanGAB29846GRB2-associated binding protein 2
INFERRED
HumanVAMP88673vesicle-associated membrane protein 8
INFERRED
HumanNDST28509N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
INFERRED
HumanLAT27462linker for activation of T cells family, member 2
INFERRED
HumanSTXBP26813syntaxin binding protein 2
INFERRED
HumanSTIM16786stromal interaction molecule 1
INFERRED
HumanPTPRC5788protein tyrosine phosphatase, receptor type, C
INFERRED
HumanPLA2G4A5321phospholipase A2, group IVA (cytosolic, calcium-dependent)
INFERRED
HumanPAK15058p21 protein (Cdc42/Rac)-activated kinase 1
INFERRED
HumanNF14763neurofibromin 1
INFERRED
HumanKIT3815v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
INFERRED
HumanINPP5D3635inositol polyphosphate-5-phosphatase, 145kDa
INFERRED
HumanFCGR2A2212Fc fragment of IgG, low affinity IIa, receptor (CD32)
INFERRED
HumanDUSP11843dual specificity phosphatase 1
INFERRED
HumanCCR31232chemokine (C-C motif) receptor 3
INFERRED
HumanRHOH399ras homolog family member H
INFERRED
HumanADORA3140adenosine A3 receptor
img Jax MP, Pubmed Id: 8962054, MOUSE PHENOTYPE ID: MGI:1861630
img Jax MP, Pubmed Id: 19805319, MOUSE PHENOTYPE ID: MGI:1341867
img Jax MP, Pubmed Id: 12817015, MOUSE PHENOTYPE ID: MGI:104847
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008763abnormal mast cell degranulation0self