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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interferon level
Debug Stats
  • ### Total Build Time: 44 ms 21.607 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 378 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 565 bytes
  • Skipping details on: CONCEPT_SYNONYM gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 578 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 594 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 2.911 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=36 ms Completed: 36 ms rowSize= 15.323 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.163 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal interferon level MP:0008750
Definition (1)
deviation from the normal levels of proteins secreted by vertebrate cells in response to a wide variety of inducers; they confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions
Parents (1)
img abnormal cytokine level MP:0008713
Children (1)
img abnormal circulating interferon level MP:0008548
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053876img abnormal cytokine level MP:0008713
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal cytokine level MP:0008713
Genes (91)

Species:
human : 91
Page Size
Current 25
  Page 1 of 4
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
INFERRED
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 37 evidence detail records.
HumanSFTPA1653509surfactant protein A1
Click here to display 37 evidence detail records.
HumanIRGM345611immunity-related GTPase family, M
INFERRED
HumanTMEM173340061transmembrane protein 173
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanRSAD291543radical S-adenosyl methionine domain containing 2
INFERRED
HumanBCL2L1283596BCL2-like 12 (proline rich)
INFERRED
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanIL2564806interleukin 25
Click here to display 37 evidence detail records.
HumanIFIH164135interferon induced with helicase C domain 1
Click here to display 37 evidence detail records.
HumanNOD264127nucleotide-binding oligomerization domain containing 2
Click here to display 37 evidence detail records.
HumanSAMSN164092SAM domain, SH3 domain and nuclear localization signals 1
INFERRED
HumanCXCL1658191chemokine (C-X-C motif) ligand 16
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanTREM254209triggering receptor expressed on myeloid cells 2
Click here to display 37 evidence detail records.
HumanTLR954106toll-like receptor 9
INFERRED
HumanTLR751284toll-like receptor 7
INFERRED
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanFOXP350943forkhead box P3
INFERRED
HumanPACSIN129993protein kinase C and casein kinase substrate in neurons 1
INFERRED
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanICOS29851inducible T-cell co-stimulator
Click here to display 37 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008750abnormal interferon level0self