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Details
Link-It Detail - Jax Mouse Phenotype - decreased interleukin-6 secretion
Debug Stats
  • ### Total Build Time: 274 ms 21.909 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 411 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 180 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 587 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 1.577 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=262 ms Completed: 262 ms rowSize= 17.474 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased interleukin-6 secretion MP:0008706
Definition (1)
reduction in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts
Synonyms (1)
"reduced IL-6 secretion" EXACT
Parents (1)
img abnormal interleukin-6 secretion MP:0008704
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal interleukin-6 secretion MP:0008704
Genes (71)

Species:
human : 71
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 107 evidence detail records.
HumanTICAM2353376toll-like receptor adaptor molecule 2
Click here to display 107 evidence detail records.
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 107 evidence detail records.
HumanCD200R1131450CD200 receptor 1
Click here to display 107 evidence detail records.
HumanSLC15A4121260solute carrier family 15 (oligopeptide transporter), member 4
Click here to display 107 evidence detail records.
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Click here to display 107 evidence detail records.
HumanCLEC6A93978C-type lectin domain family 6, member A
Click here to display 107 evidence detail records.
HumanIL3390865interleukin 33
Click here to display 107 evidence detail records.
HumanNLRC584166NLR family, CARD domain containing 5
Click here to display 107 evidence detail records.
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
Click here to display 107 evidence detail records.
HumanNFKBIZ64332nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Click here to display 107 evidence detail records.
HumanCARD964170caspase recruitment domain family, member 9
Click here to display 107 evidence detail records.
HumanIFIH164135interferon induced with helicase C domain 1
Click here to display 107 evidence detail records.
HumanNOD264127nucleotide-binding oligomerization domain containing 2
Click here to display 107 evidence detail records.
HumanSELK58515selenoprotein K
Click here to display 107 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
Click here to display 107 evidence detail records.
HumanPELI157162pellino E3 ubiquitin protein ligase 1
Click here to display 107 evidence detail records.
HumanPBK55872PDZ binding kinase
Click here to display 107 evidence detail records.
HumanIL17RB55540interleukin 17 receptor B
Click here to display 107 evidence detail records.
HumanCC2D1A54862coiled-coil and C2 domain containing 1A
Click here to display 107 evidence detail records.
HumanTOLLIP54472toll interacting protein
Click here to display 107 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
Click here to display 107 evidence detail records.
HumanPYCARD29108PYD and CARD domain containing
Click here to display 107 evidence detail records.
HumanCLEC4E26253C-type lectin domain family 4, member E
Click here to display 107 evidence detail records.
HumanCLIC425932chloride intracellular channel 4
Click here to display 107 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008706decreased interleukin-6 secretion0self