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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interleukin-6 secretion
Debug Stats
  • ### Total Build Time: 31 ms 20.535 KB
  • CONCEPT_NAME gt=10 ms Completed: 10 ms rowSize= 392 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 409 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 206 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 585 bytes
  • CONCEPT_CHILDREN gt=3 ms Completed: 3 ms rowSize= 1.035 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.575 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=17 ms Completed: 17 ms rowSize= 15.056 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.170 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal interleukin-6 secretion MP:0008704
Definition (1)
anomaly in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts
Synonyms (1)
"abnormal hepatocyte-stimulating factor secretion" EXACT
Parents (1)
img abnormal interleukin secretion MP:0008568
Children (2)
img increased interleukin-6 secretion MP:0008705
img decreased interleukin-6 secretion MP:0008706
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interleukin secretion MP:0008568
Genes (133)

Species:
human : 133
Page Size
Current 25
  Page 1 of 6
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
INFERRED
HumanTICAM2353376toll-like receptor adaptor molecule 2
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanCD200R1131450CD200 receptor 1
INFERRED
HumanSLC15A4121260solute carrier family 15 (oligopeptide transporter), member 4
INFERRED
HumanPGLYRP3114771peptidoglycan recognition protein 3
INFERRED
HumanPGLYRP2114770peptidoglycan recognition protein 2
INFERRED
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
INFERRED
HumanCLEC6A93978C-type lectin domain family 6, member A
INFERRED
HumanIL3390865interleukin 33
INFERRED
HumanNFKBID84807nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
INFERRED
HumanNLRC584166NLR family, CARD domain containing 5
INFERRED
HumanZC3H12A80149zinc finger CCCH-type containing 12A
INFERRED
HumanNLRX179671NLR family member X1
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanMMP2879148matrix metallopeptidase 28
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanATG9A79065autophagy related 9A
INFERRED
HumanNFKBIZ64332nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
INFERRED
HumanCARD964170caspase recruitment domain family, member 9
INFERRED
HumanIFIH164135interferon induced with helicase C domain 1
INFERRED
HumanNOD264127nucleotide-binding oligomerization domain containing 2
INFERRED
HumanSIGIRR59307single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
INFERRED
HumanSELK58515selenoprotein K
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008704abnormal interleukin-6 secretion0self