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Details
Link-It Detail - Jax Mouse Phenotype - decreased interleukin-4 secretion
Debug Stats
  • ### Total Build Time: 231 ms 21.892 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 454 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 182 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 587 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 1.577 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=218 ms Completed: 218 ms rowSize= 17.412 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased interleukin-4 secretion MP:0008700
Definition (1)
reduction in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells
Synonyms (1)
"reduced MCGF-2 secretion" EXACT
Parents (1)
img abnormal interleukin-4 secretion MP:0008698
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal interleukin-4 secretion MP:0008698
Genes (65)

Species:
human : 65
Page Size
Current 25
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SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
Click here to display 109 evidence detail records.
HumanCLNK116449cytokine-dependent hematopoietic cell linker
Click here to display 109 evidence detail records.
HumanSLAMF6114836SLAM family member 6
Click here to display 109 evidence detail records.
HumanRSAD291543radical S-adenosyl methionine domain containing 2
Click here to display 109 evidence detail records.
HumanNFATC2IP84901nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
Click here to display 109 evidence detail records.
HumanORAI184876ORAI calcium release-activated calcium modulator 1
Click here to display 109 evidence detail records.
HumanVTCN179679V-set domain containing T cell activation inhibitor 1
Click here to display 109 evidence detail records.
HumanRNF12879589ring finger protein 128, E3 ubiquitin protein ligase
Click here to display 109 evidence detail records.
HumanIL2564806interleukin 25
Click here to display 109 evidence detail records.
HumanCXCL1658191chemokine (C-X-C motif) ligand 16
Click here to display 109 evidence detail records.
HumanSTIM257620stromal interaction molecule 2
Click here to display 109 evidence detail records.
HumanSASH354440SAM and SH3 domain containing 3
Click here to display 109 evidence detail records.
HumanIL20RB53833interleukin 20 receptor beta
Click here to display 109 evidence detail records.
HumanIL21R50615interleukin 21 receptor
Click here to display 109 evidence detail records.
HumanICOS29851inducible T-cell co-stimulator
Click here to display 109 evidence detail records.
HumanCD27429126CD274 molecule
Click here to display 109 evidence detail records.
HumanCADM123705cell adhesion molecule 1
Click here to display 109 evidence detail records.
HumanICOSLG23308inducible T-cell co-stimulator ligand
Click here to display 109 evidence detail records.
HumanRFTN123180raftlin, lipid raft linker 1
Click here to display 109 evidence detail records.
HumanEHMT210919euchromatic histone-lysine N-methyltransferase 2
Click here to display 109 evidence detail records.
HumanBATF10538basic leucine zipper transcription factor, ATF-like
Click here to display 109 evidence detail records.
HumanEBI310148Epstein-Barr virus induced 3
Click here to display 109 evidence detail records.
HumanRAD5010111RAD50 homolog (S. cerevisiae)
Click here to display 109 evidence detail records.
HumanIL1RL19173interleukin 1 receptor-like 1
Click here to display 109 evidence detail records.
HumanCCRL29034chemokine (C-C motif) receptor-like 2
Click here to display 109 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008700decreased interleukin-4 secretion0self