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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interleukin-18 secretion
Debug Stats
  • ### Total Build Time: 7 ms 9.573 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 394 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 373 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 181 bytes
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  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
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  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 585 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 1.037 KB
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  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=6 ms Completed: 6 ms rowSize= 4.148 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.171 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal interleukin-18 secretion MP:0008683
Definition (1)
anomaly in the production or release of a cytokine which enhances the cytotoxic activity of NK cells and cytotoxic T-cells and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity
Synonyms (1)
"abnormal IL18 secretion" EXACT
Parents (1)
img abnormal interleukin secretion MP:0008568
Children (2)
img increased interleukin-18 secretion MP:0008684
img decreased interleukin-18 secretion MP:0008685
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interleukin secretion MP:0008568
Genes (8)

Species:
human : 8
SpeciesGeneGeneIdGene NameEvidence
HumanNLRP6171389NLR family, pyrin domain containing 6
INFERRED
HumanGBP5115362guanylate binding protein 5
INFERRED
HumanNLRP3114548NLR family, pyrin domain containing 3
INFERRED
HumanATG16L155054autophagy related 16-like 1 (S. cerevisiae)
INFERRED
HumanPYCARD29108PYD and CARD domain containing
INFERRED
HumanAIM29447absent in melanoma 2
INFERRED
HumanMEFV4210Mediterranean fever
INFERRED
HumanCASP4837caspase 4, apoptosis-related cysteine peptidase
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008683abnormal interleukin-18 secretion0self