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Details
Link-It Detail - Jax Mouse Phenotype - decreased circulating interleukin-18 level
Debug Stats
  • ### Total Build Time: 31 ms 12.957 KB
  • CONCEPT_NAME gt=13 ms Completed: 13 ms rowSize= 412 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 373 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 211 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=3 ms Completed: 3 ms rowSize= 596 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=2 ms Completed: 2 ms rowSize= 4.309 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=11 ms Completed: 11 ms rowSize= 5.762 KB
  • CONCEPT_XREFS gt=1 ms Completed: 1 ms rowSize= 1.180 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased circulating interleukin-18 level MP:0008636
Definition (1)
reduction in the amount in the blood of a cytokine which enhances the cytotoxic activity of NK cells and cytotoxic T-cells and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity
Synonyms (1)
"decreased circulating IFN-gamma inducing factor level" EXACT
Parents (1)
img abnormal circulating interleukin-18 level MP:0008634
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin-18 level MP:0008634
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal circulating interleukin-18 level MP:0008634
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537610img abnormal circulating interleukin-18 level MP:0008634
Genes (9)

Species:
human : 9
SpeciesGeneGeneIdGene NameEvidence
HumanNLRP6171389NLR family, pyrin domain containing 6
Click here to display 18 evidence detail records.
HumanGBP5115362guanylate binding protein 5
Click here to display 18 evidence detail records.
HumanNLRP3114548NLR family, pyrin domain containing 3
Click here to display 18 evidence detail records.
HumanPYCARD29108PYD and CARD domain containing
Click here to display 18 evidence detail records.
HumanAIM29447absent in melanoma 2
Click here to display 18 evidence detail records.
HumanIL183606interleukin 18 (interferon-gamma-inducing factor)
Click here to display 18 evidence detail records.
HumanIL1R13554interleukin 1 receptor, type I
Click here to display 18 evidence detail records.
HumanF2RL12150coagulation factor II (thrombin) receptor-like 1
Click here to display 18 evidence detail records.
HumanCASP4837caspase 4, apoptosis-related cysteine peptidase
Click here to display 18 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008636decreased circulating interleukin-18 level0self