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Details
Link-It Detail - Jax Mouse Phenotype - increased circulating interleukin-12 level
Debug Stats
  • ### Total Build Time: 73 ms 18.227 KB
  • CONCEPT_NAME gt=4 ms Completed: 4 ms rowSize= 412 bytes
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  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.180 KB
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  • Reload Stats
Jax Mouse Phenotype (1)
increased circulating interleukin-12 level MP:0008617
Definition (1)
increase in the amount in the blood of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells
Synonyms (1)
"increased circulating IL12 level" EXACT
Parents (1)
img abnormal circulating interleukin-12 level MP:0008616
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin-12 level MP:0008616
img mammalian phenotype MP:0000001img immune system phenotype MP:00053879img abnormal circulating interleukin-12 level MP:0008616
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:000537610img abnormal circulating interleukin-12 level MP:0008616
Genes (18)

Species:
human : 18
SpeciesGeneGeneIdGene NameEvidence
HumanIRGM345611immunity-related GTPase family, M
Click here to display 23 evidence detail records.
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
Click here to display 23 evidence detail records.
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
Click here to display 23 evidence detail records.
HumanTLR851311toll-like receptor 8
Click here to display 23 evidence detail records.
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
Click here to display 23 evidence detail records.
HumanSIRT323410sirtuin 3
Click here to display 23 evidence detail records.
HumanOLFM410562olfactomedin 4
Click here to display 23 evidence detail records.
HumanIL27RA9466interleukin 27 receptor, alpha
Click here to display 23 evidence detail records.
HumanTYK27297tyrosine kinase 2
Click here to display 23 evidence detail records.
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
Click here to display 23 evidence detail records.
HumanLGALS3BP3959lectin, galactoside-binding, soluble, 3 binding protein
Click here to display 23 evidence detail records.
HumanITGAD3681integrin, alpha D
Click here to display 23 evidence detail records.
HumanIL12RB23595interleukin 12 receptor, beta 2
Click here to display 23 evidence detail records.
HumanIL10RA3587interleukin 10 receptor, alpha
Click here to display 23 evidence detail records.
HumanIL103586interleukin 10
Click here to display 23 evidence detail records.
HumanIFNAR13454interferon (alpha, beta and omega) receptor 1
Click here to display 23 evidence detail records.
HumanELAVL11994ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
Click here to display 23 evidence detail records.
HumanAPOE348apolipoprotein E
Click here to display 23 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008617increased circulating interleukin-12 level0self