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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interleukin-12 level
Debug Stats
  • ### Total Build Time: 52 ms 22.817 KB
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  • CONCEPT_GENES gt=34 ms Completed: 34 ms rowSize= 14.046 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal circulating interleukin-12 level MP:0008616
Definition (1)
anomaly in the amount in the blood of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells
Synonyms (1)
"abnormal circulating interleukin-12 p70 level" EXACT
Parents (1)
img abnormal circulating interleukin level MP:0008588
Children (3)
img increased circulating interleukin-12 level MP:0008617
img decreased circulating interleukin-12 level MP:0008618
img abnormal circulating interleukin-12a level MP:0008643
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin level MP:0008588
Genes (28)

Species:
human : 28
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanIRGM345611immunity-related GTPase family, M
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanTLR851311toll-like receptor 8
INFERRED
HumanIL2250616interleukin 22
INFERRED
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanSIRT323410sirtuin 3
INFERRED
HumanOLFM410562olfactomedin 4
INFERRED
HumanAPBA39546amyloid beta (A4) precursor protein-binding, family A, member 3
INFERRED
HumanIL27RA9466interleukin 27 receptor, alpha
INFERRED
HumanRPS6KA59252ribosomal protein S6 kinase, 90kDa, polypeptide 5
INFERRED
HumanTYK27297tyrosine kinase 2
INFERRED
HumanTRPM27226transient receptor potential cation channel, subfamily M, member 2
INFERRED
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
INFERRED
HumanNPY1R4886neuropeptide Y receptor Y1
INFERRED
HumanLGALS3BP3959lectin, galactoside-binding, soluble, 3 binding protein
INFERRED
HumanITGAD3681integrin, alpha D
INFERRED
HumanIL12RB23595interleukin 12 receptor, beta 2
INFERRED
HumanIL12A3592interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
INFERRED
HumanIL10RA3587interleukin 10 receptor, alpha
INFERRED
HumanIL103586interleukin 10
INFERRED
HumanIL63569interleukin 6 (interferon, beta 2)
INFERRED
HumanIFNGR13459interferon gamma receptor 1
INFERRED
HumanIFNAR13454interferon (alpha, beta and omega) receptor 1
INFERRED
HumanFLT32322fms-related tyrosine kinase 3
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008616abnormal circulating interleukin-12 level0self