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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interleukin-1 level
Debug Stats
  • ### Total Build Time: 32 ms 23.130 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 408 bytes
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Jax Mouse Phenotype (1)
abnormal circulating interleukin-1 level MP:0008589
Definition (1)
anomaly in the amount in the blood of a soluble factor produced by monocytes, macrophages and other cells, which activates T-lymphocytes and potentiates their response to mitogens or antigens
Synonyms (1)
"abnormal circulating T helper factor level" EXACT
Parents (1)
img abnormal circulating interleukin level MP:0008588
Children (4)
img abnormal circulating interleukin-1 beta level MP:0008640
img abnormal circulating interleukin-1 alpha level MP:0008637
img decreased circulating interleukin-1 level MP:0008592
img increased circulating interleukin-1 level MP:0008591
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053769img abnormal circulating interleukin level MP:0008588
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating interleukin level MP:0008588
Genes (45)

Species:
human : 45
Page Size
Current 25
  Page 1 of 2
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGBP5115362guanylate binding protein 5
INFERRED
HumanNLRP3114548NLR family, pyrin domain containing 3
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanTREM154210triggering receptor expressed on myeloid cells 1
INFERRED
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanIL2250616interleukin 22
INFERRED
HumanPILRB29990paired immunoglobin-like type 2 receptor beta
INFERRED
HumanTBK129110TANK-binding kinase 1
INFERRED
HumanPYCARD29108PYD and CARD domain containing
INFERRED
HumanSMG123049SMG1 phosphatidylinositol 3-kinase-related kinase
INFERRED
HumanIL27RA9466interleukin 27 receptor, alpha
INFERRED
HumanSOCS28835suppressor of cytokine signaling 2
INFERRED
HumanSTX118676syntaxin 11
INFERRED
HumanNCOA38202nuclear receptor coactivator 3
INFERRED
HumanTNFRSF1A7132tumor necrosis factor receptor superfamily, member 1A
INFERRED
HumanTNF7124tumor necrosis factor
INFERRED
HumanTLR27097toll-like receptor 2
INFERRED
HumanTHBD7056thrombomodulin
INFERRED
HumanBRD26046bromodomain containing 2
INFERRED
HumanRAB27A5873RAB27A, member RAS oncogene family
INFERRED
HumanPTPN65777protein tyrosine phosphatase, non-receptor type 6
INFERRED
HumanPRKCE5581protein kinase C, epsilon
INFERRED
HumanPRF15551perforin 1 (pore forming protein)
INFERRED
HumanPCSK15122proprotein convertase subtilisin/kexin type 1
INFERRED
HumanNFKBIB4793nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008589abnormal circulating interleukin-1 level0self