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Details
Link-It Detail - Jax Mouse Phenotype - abnormal circulating interleukin level
Debug Stats
  • ### Total Build Time: 76 ms 36.464 KB
  • CONCEPT_NAME gt=3 ms Completed: 3 ms rowSize= 404 bytes
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  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 187 bytes
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  • CONCEPT_CHILDREN gt=7 ms Completed: 7 ms rowSize= 8.988 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=5 ms Completed: 5 ms rowSize= 6.974 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=49 ms Completed: 49 ms rowSize= 17.129 KB
  • CONCEPT_XREFS gt=3 ms Completed: 3 ms rowSize= 1.176 KB
  • CONCEPT_ANCILLARY gt=1 ms Completed: 1 ms rowSize= 14 bytes
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Jax Mouse Phenotype (1)
abnormal circulating interleukin level MP:0008588
Definition (1)
anomaly in the amount in the blood of soluble factors which stimulate growth-related activities of leukocytes as well as other cell types; they enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli
Synonyms (1)
"abnormal circulating IL level" EXACT
Parents (2)
img abnormal interleukin level MP:0008751
img abnormal circulating cytokine level MP:0010210
Children (19)
img abnormal circulating interleukin-10 level MP:0008590
img abnormal circulating interleukin-21 level MP:0009059
img abnormal circulating interleukin-6 level MP:0008595
img abnormal circulating interleukin-15 level MP:0008610
img abnormal circulating interleukin-1 level MP:0008589
img abnormal circulating interleukin-3 level MP:0008622
img abnormal circulating interleukin-9 level MP:0008628
img abnormal circulating interleukin-7 level MP:0008604
img abnormal circulating interleukin-12 level MP:0008616
img abnormal circulating interleukin-23 level MP:0008619
img abnormal circulating interleukin-16 level MP:0008631
img abnormal circulating interleukin-18 level MP:0008634
img abnormal circulating interleukin-2 level MP:0008598
img abnormal circulating interleukin-13 level MP:0008607
img abnormal circulating interleukin-8 level MP:0011713
img abnormal circulating interleukin-4 level MP:0008601
img abnormal circulating interleukin-12b level MP:0008646
img abnormal circulating interleukin-17 level MP:0008613
img abnormal circulating interleukin-5 level MP:0008625
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interleukin level MP:0008751
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal interleukin level MP:0008751
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053767img abnormal circulating cytokine level MP:0010210
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal circulating cytokine level MP:0010210
img mammalian phenotype MP:0000001img homeostasis/metabolism phenotype MP:00053768img abnormal circulating cytokine level MP:0010210
Genes (179)

Species:
human : 179
Page Size
Current 25
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Current 1
SpeciesGeneGeneIdGene NameEvidence
HumanGIMAP1-GIMAP5100527949
INFERRED
HumanCASP12100506742caspase 12 (gene/pseudogene)
INFERRED
HumanIRGM345611immunity-related GTPase family, M
INFERRED
HumanTMEM173340061transmembrane protein 173
INFERRED
HumanTAB3257397TGF-beta activated kinase 1/MAP3K7 binding protein 3
INFERRED
HumanIL27246778interleukin 27
INFERRED
HumanNLRC3197358NLR family, CARD domain containing 3
INFERRED
HumanNLRP6171389NLR family, pyrin domain containing 6
INFERRED
HumanBBS12166379Bardet-Biedl syndrome 12
INFERRED
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanGBP5115362guanylate binding protein 5
INFERRED
HumanSLAMF6114836SLAM family member 6
INFERRED
HumanPGLYRP2114770peptidoglycan recognition protein 2
INFERRED
HumanTIRAP114609toll-interleukin 1 receptor (TIR) domain containing adaptor protein
INFERRED
HumanNLRP3114548NLR family, pyrin domain containing 3
INFERRED
HumanTSLP85480thymic stromal lymphopoietin
INFERRED
HumanNFATC2IP84901nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
INFERRED
HumanCARD1184433caspase recruitment domain family, member 11
INFERRED
HumanNLRX179671NLR family member X1
INFERRED
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
INFERRED
HumanRNF12879589ring finger protein 128, E3 ubiquitin protein ligase
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanCLEC7A64581C-type lectin domain family 7, member A
img Jax MP, Pubmed Id: 22038916, MOUSE PHENOTYPE ID: MGI:1861431
img Jax MP, Pubmed Id: 18412165, MOUSE PHENOTYPE ID: MGI:1354171
img Jax MP, Pubmed Id: 9500796, MOUSE PHENOTYPE ID: MGI:103034
HumanNOD264127nucleotide-binding oligomerization domain containing 2
INFERRED
HumanCXCL1658191chemokine (C-X-C motif) ligand 16
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008588abnormal circulating interleukin level0self