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Details
Link-It Detail - Jax Mouse Phenotype - decreased interferon-beta secretion
Debug Stats
  • ### Total Build Time: 26 ms 14.263 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 398 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 396 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 186 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=1 ms Completed: 1 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=4 ms Completed: 4 ms rowSize= 589 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=3 ms Completed: 3 ms rowSize= 1.579 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=18 ms Completed: 18 ms rowSize= 9.826 KB
  • CONCEPT_XREFS gt=0 Completed: 0 ms rowSize= 1.173 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
decreased interferon-beta secretion MP:0008565
Definition (1)
reduction in the production or release of one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA with antiviral, antiproliferative, and immunomodulating activity
Synonyms (1)
"decreased IFN-beta secretion" EXACT
Parents (1)
img abnormal interferon-beta secretion MP:0008558
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053878img abnormal interferon-beta secretion MP:0008558
Genes (16)

Species:
human : 16
SpeciesGeneGeneIdGene NameEvidence
HumanTICAM1148022toll-like receptor adaptor molecule 1
Click here to display 31 evidence detail records.
HumanCD200R1131450CD200 receptor 1
Click here to display 31 evidence detail records.
HumanRSAD291543radical S-adenosyl methionine domain containing 2
Click here to display 31 evidence detail records.
HumanNLRC584166NLR family, CARD domain containing 5
Click here to display 31 evidence detail records.
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
Click here to display 31 evidence detail records.
HumanMAVS57506mitochondrial antiviral signaling protein
Click here to display 31 evidence detail records.
HumanPELI157162pellino E3 ubiquitin protein ligase 1
Click here to display 31 evidence detail records.
HumanCC2D1A54862coiled-coil and C2 domain containing 1A
Click here to display 31 evidence detail records.
HumanTLR954106toll-like receptor 9
Click here to display 31 evidence detail records.
HumanIRAK451135interleukin-1 receptor-associated kinase 4
Click here to display 31 evidence detail records.
HumanTBK129110TANK-binding kinase 1
Click here to display 31 evidence detail records.
HumanTRADD8717TNFRSF1A-associated via death domain
Click here to display 31 evidence detail records.
HumanIRF73665interferon regulatory factor 7
Click here to display 31 evidence detail records.
HumanIRF33661interferon regulatory factor 3
Click here to display 31 evidence detail records.
HumanIFNAR13454interferon (alpha, beta and omega) receptor 1
Click here to display 31 evidence detail records.
HumanHMOX13162heme oxygenase (decycling) 1
Click here to display 31 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008565decreased interferon-beta secretion0self