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Details
Link-It Detail - Jax Mouse Phenotype - increased tumor necrosis factor secretion
Debug Stats
  • ### Total Build Time: 565 ms 22.259 KB
  • CONCEPT_NAME gt=0 Completed: 0 ms rowSize= 410 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 512 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 187 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=0 Completed: 0 ms rowSize= 595 bytes
  • CONCEPT_CHILDREN gt=0 Completed: 0 ms rowSize= 8 bytes
  • CONCEPT_ANCESTRAL_ROOTS gt=0 Completed: 0 ms rowSize= 1.585 KB
  • CONCEPT_RELATIONSHIPS gt=0 Completed: 0 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=562 ms Completed: 562 ms rowSize= 17.679 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.179 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
increased tumor necrosis factor secretion MP:0008560
Definition (1)
increase in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
Synonyms (1)
"increased cachectin secretion" EXACT
Parents (1)
img abnormal tumor necrosis factor secretion MP:0008556
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal tumor necrosis factor secretion MP:0008556
Genes (84)

Species:
human : 84
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SpeciesGeneGeneIdGene NameEvidence
HumanCCR2729230chemokine (C-C motif) receptor 2
Click here to display 121 evidence detail records.
HumanTREML1340205triggering receptor expressed on myeloid cells-like 1
Click here to display 121 evidence detail records.
HumanNLRC3197358NLR family, CARD domain containing 3
Click here to display 121 evidence detail records.
HumanB3GNT6192134UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
Click here to display 121 evidence detail records.
HumanCD200R1131450CD200 receptor 1
Click here to display 121 evidence detail records.
HumanTIMD491937T-cell immunoglobulin and mucin domain containing 4
Click here to display 121 evidence detail records.
HumanUNC93B181622unc-93 homolog B1 (C. elegans)
Click here to display 121 evidence detail records.
HumanZC3H12A80149zinc finger CCCH-type containing 12A
Click here to display 121 evidence detail records.
HumanTNFAIP8L279626tumor necrosis factor, alpha-induced protein 8-like 2
Click here to display 121 evidence detail records.
HumanMMP2879148matrix metallopeptidase 28
Click here to display 121 evidence detail records.
HumanPBK55872PDZ binding kinase
Click here to display 121 evidence detail records.
HumanUACA55075uveal autoantigen with coiled-coil domains and ankyrin repeats
Click here to display 121 evidence detail records.
HumanFOXP350943forkhead box P3
Click here to display 121 evidence detail records.
HumanTBX2130009T-box 21
Click here to display 121 evidence detail records.
HumanCD27429126CD274 molecule
Click here to display 121 evidence detail records.
HumanTBK129110TANK-binding kinase 1
Click here to display 121 evidence detail records.
HumanPYCARD29108PYD and CARD domain containing
Click here to display 121 evidence detail records.
HumanRABGEF127342RAB guanine nucleotide exchange factor (GEF) 1
Click here to display 121 evidence detail records.
HumanSIT127240signaling threshold regulating transmembrane adaptor 1
Click here to display 121 evidence detail records.
HumanCD300A11314CD300a molecule
Click here to display 121 evidence detail records.
HumanDUSP1011221dual specificity phosphatase 10
Click here to display 121 evidence detail records.
HumanIRAK311213interleukin-1 receptor-associated kinase 3
Click here to display 121 evidence detail records.
HumanMAP4K111184mitogen-activated protein kinase kinase kinase kinase 1
Click here to display 121 evidence detail records.
HumanTRAFD110906TRAF-type zinc finger domain containing 1
Click here to display 121 evidence detail records.
HumanB3GNT210678UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Click here to display 121 evidence detail records.
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008560increased tumor necrosis factor secretion0self