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Details
Link-It Detail - Jax Mouse Phenotype - abnormal interferon-beta secretion
Debug Stats
  • ### Total Build Time: 25 ms 15.511 KB
  • CONCEPT_NAME gt=5 ms Completed: 5 ms rowSize= 396 bytes
  • CONCEPT_SOLR_HIT_STATS gt=0 Completed: 0 ms rowSize= 14 bytes
  • CONCEPT_DEFINITION gt=0 Completed: 0 ms rowSize= 394 bytes
  • CONCEPT_SYNONYM gt=0 Completed: 0 ms rowSize= 185 bytes
  • Skipping details on: CONCEPT_TEXT gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_SEMANTIC_TYPE gt=0 Completed: 0 ms rowSize= 14 bytes
  • Skipping details on: CONCEPT_NAMESPACE gt=NONE 0 Completed: 0 ms rowSize= 0 bytes
  • CONCEPT_PARENTS gt=2 ms Completed: 2 ms rowSize= 584 bytes
  • CONCEPT_CHILDREN gt=2 ms Completed: 2 ms rowSize= 1.039 KB
  • CONCEPT_ANCESTRAL_ROOTS gt=1 ms Completed: 1 ms rowSize= 1.574 KB
  • CONCEPT_RELATIONSHIPS gt=1 ms Completed: 1 ms rowSize= 106 bytes
  • CONCEPT_GENES gt=12 ms Completed: 12 ms rowSize= 10.059 KB
  • CONCEPT_XREFS gt=2 ms Completed: 2 ms rowSize= 1.172 KB
  • CONCEPT_ANCILLARY gt=0 Completed: 0 ms rowSize= 14 bytes
  • Reload Stats
Jax Mouse Phenotype (1)
abnormal interferon-beta secretion MP:0008558
Definition (1)
anomaly in the production or release of one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA with antiviral, antiproliferative, and immunomodulating activity
Synonyms (1)
"abnormal beta-IFN secretion" EXACT
Parents (1)
img abnormal interferon secretion MP:0008555
Children (2)
img increased interferon-beta secretion MP:0008564
img decreased interferon-beta secretion MP:0008565
Ancestral Roots
RootRoot Plus OneDepthParent
img mammalian phenotype MP:0000001img immune system phenotype MP:00053877img abnormal interferon secretion MP:0008555
Genes (21)

Species:
human : 21
SpeciesGeneGeneIdGene NameEvidence
HumanTICAM1148022toll-like receptor adaptor molecule 1
INFERRED
HumanCD200R1131450CD200 receptor 1
INFERRED
HumanRSAD291543radical S-adenosyl methionine domain containing 2
INFERRED
HumanNLRC584166NLR family, CARD domain containing 5
INFERRED
HumanNLRX179671NLR family member X1
INFERRED
HumanDHX5879132DEXH (Asp-Glu-X-His) box polypeptide 58
INFERRED
HumanATG9A79065autophagy related 9A
INFERRED
HumanMAVS57506mitochondrial antiviral signaling protein
INFERRED
HumanPELI157162pellino E3 ubiquitin protein ligase 1
INFERRED
HumanCC2D1A54862coiled-coil and C2 domain containing 1A
INFERRED
HumanTLR954106toll-like receptor 9
INFERRED
HumanIRAK451135interleukin-1 receptor-associated kinase 4
INFERRED
HumanTBK129110TANK-binding kinase 1
INFERRED
HumanPYCARD29108PYD and CARD domain containing
INFERRED
HumanAIM29447absent in melanoma 2
INFERRED
HumanTRADD8717TNFRSF1A-associated via death domain
INFERRED
HumanKHSRP8570KH-type splicing regulatory protein
INFERRED
HumanIRF73665interferon regulatory factor 7
INFERRED
HumanIRF33661interferon regulatory factor 3
INFERRED
HumanIFNAR13454interferon (alpha, beta and omega) receptor 1
INFERRED
HumanHMOX13162heme oxygenase (decycling) 1
INFERRED
XRefs (1)

XRef Types:
mp : 1


ToppGene Datasets:
none : 1
ToppGene DatasetsXRef TypeXRef IdXRefValuesSourceTop % Rank
MPimg MP:0008558abnormal interferon-beta secretion0self